A0A7L5UF89 · A0A7L5UF89_9LACO

Function

function

Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).

Catalytic activity

Pathway

Pyrimidine metabolism; UMP biosynthesis via de novo pathway; UMP from orotate: step 2/2.

Features

Showing features for binding site, active site.

124020406080100120140160180200220240
Type
IDPosition(s)Description
Binding site11substrate
Binding site35substrate
Active site62For OMPdecase activity
Binding site62-71substrate
Active site64For OMPdecase activity
Active site64Proton donor
Active site67For OMPdecase activity
Binding site126substrate
Binding site188substrate
Binding site197substrate
Binding site217substrate
Binding site218substrate

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular Functionorotidine-5'-phosphate decarboxylase activity
Biological Process'de novo' pyrimidine nucleobase biosynthetic process
Biological Process'de novo' UMP biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Orotidine 5'-phosphate decarboxylase
  • EC number
  • Alternative names
    • OMP decarboxylase
      (OMPDCase
      ; OMPdecase
      )

Gene names

    • Name
      pyrF
    • ORF names
      GTO83_00245

Organism names

  • Taxonomic identifier
  • Strain
    • 3B(2020)
  • Taxonomic lineage
    Bacteria > Bacillota > Bacilli > Lactobacillales > Lactobacillaceae > Lactobacillus

Accessions

  • Primary accession
    A0A7L5UF89

Proteomes

Subcellular Location

Interaction

Subunit

Homodimer.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain5-233Orotidine 5'-phosphate decarboxylase

Sequence similarities

Belongs to the OMP decarboxylase family. Type 1 subfamily.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    240
  • Mass (Da)
    25,609
  • Last updated
    2021-04-07 v1
  • Checksum
    291349F23944DA35
MQRFAPMVAIDVPTKEEAVALFDQLAMTTPKPIVKLGMELYYTAGPEIISLARQRGFKVFVDLKLYDIPNTVGRAMKGLGKLGASFVTVHAAGGKEMLQAALDGLQTGAQAANLPLPNLLAITELTSINQRIMNEEQGIPGELVTTVQRYAKLADKVGLAGVVCSAQEVEAIRQVTRADFYCVTPGIRPVGSAKGDQKRVVTPAQAHQLGANAIVCGRPITQAESVSDAYEAIAQEFLEG

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP047410
EMBL· GenBank· DDBJ
QLL69115.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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