A0A7L4PNJ1 · A0A7L4PNJ1_9EURY
- ProteinDNA polymerase II large subunit
- GenepolC
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids1116 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase.
Catalytic activity
- a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1)
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | DNA binding | |
Molecular Function | DNA-directed DNA polymerase activity | |
Molecular Function | single-stranded DNA 3'-5' DNA exonuclease activity | |
Biological Process | DNA catabolic process | |
Biological Process | DNA-templated DNA replication |
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameDNA polymerase II large subunit
- EC number
- Short namesPol II
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageArchaea > Euryarchaeota > Stenosarchaea group > Candidatus Methanofastidiosia
Accessions
- Primary accessionA0A7L4PNJ1
Proteomes
Interaction
Subunit
Heterodimer of a large subunit and a small subunit.
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 4-869 | DNA polymerase II large subunit DP2 N-terminal | ||||
Sequence: SYFNSLESEGRRAYEIAQEARKKGLDPSPSVEIPLAADMAGRIEGIVGPKGVAKKIKELDMQGHSREKIAIIIADEIIAEKYSKKNSKEKLAEQAVRTGLAILTEGIVSAPLEGISDVKIKTNFDGTDYLALYFAGPIRSAGGTAAALSVLLGDYIRKRLGLSKYKATEEEIQRFIEEIELYERGKTNLQYRPSNKEVIVALSNIPIEITGESTEEIEVSGYRNLERIETNKVRGGALLALAEGVIQKSKKIEKVLKVFELEGWDFLKDMKKEEKKQSDDNNEKIKANWKYLSDLLAGRPVIAHPSSKGGFRIRYGRSRNTGFAAWGYHPAAMTIVNGFIAVGTQLKTERPGKATVSMPVDSILPPFVKFKDQSCDWLYSYENIKPEDVEEVIFLGDVLIAYGDFVENNHLLLPSGYVEEWWELDFEKALNEKGDNLTNFKDILEGNRIPEVEEAIEISKKYDIPLHPKYNLFWSYISTDDLDYLINYNRYTINENTILFNLEDGSRIKDILENLCVPHQVSNGTVKIDSHILKLILSGKQPYGDSVLDRVSSLLEIPVRDAIPTTVGCRMGRPEKAKERKMSPPVHVLFPIGMSGGSTRSIIKASQKNYIEVESVNKRCPKCNTKTHLTKCPDCESMTKMYMSCSHQTCSYEGSSVVSEKCPECGSPLRVYSRKKVNLKDDLSLALLNVGYALPKEVKGVQGMSSEYKIPEPIEKGIIRASNDIFVFKDGTCRYDATDAPLTHFIPREANVSIEKLKGLGYIKDYQGNELTDENQILELNVQDIIIPKDSISYLYKVSKFIDGELEKLYGLKSYYNLEKEEDLIGQLVVGLAPHTSAGTIGRIVGFTDTKVVYAHPYFHAAKRRN |
Sequence similarities
Belongs to the archaeal DNA polymerase II family.
Family and domain databases
Sequence
- Sequence statusComplete
- Length1,116
- Mass (Da)125,709
- Last updated2021-04-07 v1
- Checksum0C85F23A7280272D