A0A7L4ARI5 · A0A7L4ARI5_9CHAR

Function

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Features

Showing features for binding site, active site.

TypeIDPosition(s)Description
Binding site292-293substrate
Active site354Phosphocysteine intermediate
Binding site354-360substrate

GO annotations

AspectTerm
Cellular Componentfilopodium
Cellular Componentlate endosome
Cellular Componentplasma membrane
Cellular Componentruffle
Cellular Componentsarcomere
Molecular Functionphosphatidylinositol-3,5-bisphosphate 3-phosphatase activity
Molecular Functionphosphatidylinositol-3-phosphate phosphatase activity
Molecular Functionphosphoprotein phosphatase activity
Biological Processlipid metabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Myotubularin
  • EC number
  • Alternative names
    • Phosphatidylinositol-3,5-bisphosphate 3-phosphatase
    • Phosphatidylinositol-3-phosphate phosphatase

Gene names

    • Name
      Mtm1
    • ORF names
      PHASIM_R13216

Organism names

  • Taxonomic identifier
  • Strain
    • B10K-DU-009-16
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Archelosauria > Archosauria > Dinosauria > Saurischia > Theropoda > Coelurosauria > Aves > Neognathae > Charadriiformes > Laridae > Phaetusa

Accessions

  • Primary accession
    A0A7L4ARI5

Proteomes

Subcellular Location

Cell membrane
; Peripheral membrane protein
Cell projection, filopodium
Cell projection, ruffle
Cytoplasm, myofibril, sarcomere
Endosome
Late endosome

Keywords

Family & Domains

Features

Showing features for domain, region.

TypeIDPosition(s)Description
Domain142-517Myotubularin phosphatase
Domain323-385Tyrosine specific protein phosphatases
Region560-582Disordered

Sequence similarities

Family and domain databases

Sequence

  • Sequence status
    Fragment
  • Length
    582
  • Mass (Da)
    67,517
  • Last updated
    2021-04-07 v1
  • Checksum
    0FCFB46FEE7043A7
TLKDGTNWEQNEEIPRLPGETRVTDKDVIYMCPFNGPVKGRVYITNYRLYLRSVENDPVVILNVPLGVISRTEKMGGASSRGENSYGLDITCKDMRNLRFALKQEGHSRRDIFEVLTKYAFPQSHNLLFFAFANEEKFSENGWMVYNPMSEYRRQGLPNERWRVTFINEHYGLCDTYPSLLVVPYNATDDDLKKVAAFRSRNRIPVLSWIHPETQAVIMRCSQPLVGMSGKRNKDDERYLDIIREANGQISKLTIYDARPNVNAVANKATGGGYEGEDAYPNAELFFLDIHNIHVMRESLKKLKDIVYPNVEESHWLSSLESTHWLEHIKLVLTGAIQVADKVSSGRSSVLVHCSDGWDRTAQLTSLAMLMLDSYYRTIEGFEVLVQKEWISFGHKFASRIGHGDKNHADADRSPIFLQFIDCVWQMSKQFPTAFEFNEQFLITILDHLYSCRFGTFLYNSESLREKEKVTEKTLSLWSLVNSEKSKYTNPFYTKELNRALYPVASMRHLELWVNYYIRWNPRIRQQQPNPVEQRYMELLALRDDYMRRLEELQITNNSKISNSSASSASPSQMMSQVQTHF

Features

Showing features for non-terminal residue.

TypeIDPosition(s)Description
Non-terminal residue1
Non-terminal residue582

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
VZZW01000048
EMBL· GenBank· DDBJ
NXW27330.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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