A0A7L4ARI5 · A0A7L4ARI5_9CHAR
- ProteinMyotubularin
- GeneMtm1
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids582 (go to sequence)
- Protein existenceInferred from homology
- Annotation score4/5
Function
Catalytic activity
- 1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-phosphate) + H2O = 1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol-5-phosphate) + phosphate
- 1,2-dioctanoyl-sn-glycero-3-phospho-(1-D-myo-inositol-3-phosphate) + H2O = 1,2-dioctanoyl-sn-glycero-3-phospho-(1D-myo-inositol) + phosphate
- 1,2-dioctanoyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-bisphosphate) + H2O = 1,2-dioctanoyl-sn-glycero-3-phospho-(1D-myo-inositol-5-phosphate) + phosphate
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Binding site | 292-293 | substrate | ||||
Sequence: NI | ||||||
Active site | 354 | Phosphocysteine intermediate | ||||
Sequence: C | ||||||
Binding site | 354-360 | substrate | ||||
Sequence: CSDGWDR |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | filopodium | |
Cellular Component | late endosome | |
Cellular Component | plasma membrane | |
Cellular Component | ruffle | |
Cellular Component | sarcomere | |
Molecular Function | phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity | |
Molecular Function | phosphatidylinositol-3-phosphate phosphatase activity | |
Molecular Function | phosphoprotein phosphatase activity | |
Biological Process | lipid metabolic process |
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameMyotubularin
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Archelosauria > Archosauria > Dinosauria > Saurischia > Theropoda > Coelurosauria > Aves > Neognathae > Charadriiformes > Laridae > Phaetusa
Accessions
- Primary accessionA0A7L4ARI5
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Cell membrane ; Peripheral membrane protein
Keywords
- Cellular component
Structure
Family & Domains
Features
Showing features for domain, region.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 142-517 | Myotubularin phosphatase | ||||
Sequence: GWMVYNPMSEYRRQGLPNERWRVTFINEHYGLCDTYPSLLVVPYNATDDDLKKVAAFRSRNRIPVLSWIHPETQAVIMRCSQPLVGMSGKRNKDDERYLDIIREANGQISKLTIYDARPNVNAVANKATGGGYEGEDAYPNAELFFLDIHNIHVMRESLKKLKDIVYPNVEESHWLSSLESTHWLEHIKLVLTGAIQVADKVSSGRSSVLVHCSDGWDRTAQLTSLAMLMLDSYYRTIEGFEVLVQKEWISFGHKFASRIGHGDKNHADADRSPIFLQFIDCVWQMSKQFPTAFEFNEQFLITILDHLYSCRFGTFLYNSESLREKEKVTEKTLSLWSLVNSEKSKYTNPFYTKELNRALYPVASMRHLELWVNYY | ||||||
Domain | 323-385 | Tyrosine specific protein phosphatases | ||||
Sequence: THWLEHIKLVLTGAIQVADKVSSGRSSVLVHCSDGWDRTAQLTSLAMLMLDSYYRTIEGFEVL | ||||||
Region | 560-582 | Disordered | ||||
Sequence: KISNSSASSASPSQMMSQVQTHF |
Sequence similarities
Family and domain databases
Sequence
- Sequence statusFragment
- Length582
- Mass (Da)67,517
- Last updated2021-04-07 v1
- Checksum0FCFB46FEE7043A7
Features
Showing features for non-terminal residue.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Non-terminal residue | 1 | |||||
Sequence: T | ||||||
Non-terminal residue | 582 | |||||
Sequence: F |
Keywords
- Technical term