A0A7L3XF21 · A0A7L3XF21_9AVES
- ProteinCyanocobalamin reductase / alkylcobalamin dealkylase
- GeneMmachc
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids232 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
Catalytic activity
- 2 cob(II)alamin-[cyanocobalamin reductase] + 2 hydrogen cyanide + NADP+ = 2 cyanocob(III)alamin + 2 apo-[cyanocobalamin reductase] + NADPH + H+This reaction proceeds in the backward direction.
2 RHEA-COMP:14717 CHEBI:16304 Position: ACHEBI:83228 Position: B+ 2 CHEBI:18407 + CHEBI:58349 = 2 CHEBI:17439 + 2 RHEA-COMP:14718 + CHEBI:57783 + CHEBI:15378
Cofactor
Protein has several cofactor binding sites:
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | cobalamin binding | |
Molecular Function | cyanocobalamin reductase (cyanide-eliminating) (NADP+) activity | |
Molecular Function | demethylase activity | |
Molecular Function | FAD binding | |
Biological Process | cobalamin metabolic process |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameCyanocobalamin reductase / alkylcobalamin dealkylase
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Archelosauria > Archosauria > Dinosauria > Saurischia > Theropoda > Coelurosauria > Aves > Neognathae > Neoaves > Aequornithes > Procellariiformes > Procellariidae > Calonectris
Accessions
- Primary accessionA0A7L3XF21
Proteomes
Subcellular Location
PTM/Processing
Features
Showing features for signal, chain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Signal | 1-24 | ||||
Chain | PRO_5029541110 | 25-232 | Cyanocobalamin reductase / alkylcobalamin dealkylase | ||
Structure
Sequence
- Sequence statusFragment
- Length232
- Mass (Da)27,118
- Last updated2021-04-07 v1
- MD5 Checksum257A45543FD83549A2B0A0FFE1250492
Features
Showing features for non-terminal residue.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Non-terminal residue | 1 | ||||
Non-terminal residue | 232 | ||||
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
VZUG01010357 EMBL· GenBank· DDBJ | NXV87788.1 EMBL· GenBank· DDBJ | Genomic DNA |