A0A7L3CQC5 · A0A7L3CQC5_PLUSO

Function

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

  • 1-(beta-D-galactosyl)-N-dodecanoylsphing-4-enine + cholesterol = cholesteryl 3-beta-D-galactoside + N-dodecanoylsphing-4-enine
    This reaction proceeds in the forward
    and the backward
    directions.
  • a beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine + H2O = an N-acylsphing-4-enine + D-galactose
    This reaction proceeds in the forward direction.
    EC:3.2.1.46 (UniProtKB | ENZYME | Rhea)
  • a beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine + cholesterol = an N-acylsphing-4-enine + cholesteryl 3-beta-D-galactoside
    This reaction proceeds in the forward
    and the backward
    directions.
  • a beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine + H2O = an N-acylsphing-4-enine + D-glucose
    This reaction proceeds in the forward direction.
    EC:3.2.1.45 (UniProtKB | ENZYME | Rhea)
  • a beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine + cholesterol = an N-acylsphing-4-enine + cholesteryl 3-beta-D-glucoside
    This reaction proceeds in the forward
    and the backward
    directions.
  • a beta-D-xylosyl-(1<->1')-N-acylsphing-4-enine + cholesterol = an N-acylsphing-4-enine + cholesteryl 3-beta-D-xyloside
    This reaction proceeds in the forward direction.
  • beta-D-glucosyl-(1<->1')-N-(15Z-tetracosenoyl)-sphing-4-enine + cholesterol = cholesteryl 3-beta-D-glucoside + N-(15Z-tetracosenoyl)-sphing-4-enine
    This reaction proceeds in the forward
    and the backward
    directions.
  • beta-D-glucosyl-(1<->1)-N-octadecanoylsphing-4-enine + cholesterol = cholesteryl 3-beta-D-glucoside + N-octadecanoylsphing-4-enine
    This reaction proceeds in the forward
    and the backward
    directions.
  • beta-D-glucosyl-N-(9Z-octadecenoyl)-sphing-4E-enine + cholesterol = cholesteryl 3-beta-D-glucoside + N-(9Z-octadecenoyl)-sphing-4-enine
    This reaction proceeds in the forward
    and the backward
    directions.
  • beta-D-glucosyl-N-dodecanoylsphing-4-enine + cholesterol = cholesteryl 3-beta-D-glucoside + N-dodecanoylsphing-4-enine
    This reaction proceeds in the forward
    and the backward
    directions.
  • beta-D-glucosyl-N-octanoylsphing-4E-enine + cholesterol = cholesteryl 3-beta-D-glucoside + N-octanoylsphing-4-enine
    This reaction proceeds in the forward
    and the backward
    directions.
  • beta-D-xylosyl-(1<->1')-N-(9Z-octadecenoyl)-sphing-4-enine + cholesterol = cholesteryl 3-beta-D-xyloside + N-(9Z-octadecenoyl)-sphing-4-enine
    This reaction proceeds in the forward direction.
  • cholesteryl 3-beta-D-glucoside + H2O = cholesterol + D-glucose
    This reaction proceeds in the forward direction.

Pathway

Steroid metabolism; cholesterol metabolism.

GO annotations

AspectTerm
Cellular Componentlysosomal membrane
Molecular Functionglucosylceramidase activity
Biological Processcholesterol metabolic process
Biological Processglucosylceramide catabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Glucosylceramidase
  • EC number

Gene names

    • Name
      Gba_3
    • ORF names
      PLUSOC_R13136

Organism names

  • Taxonomic identifier
  • Strain
    • B10K-DU-012-14
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Archelosauria > Archosauria > Dinosauria > Saurischia > Theropoda > Coelurosauria > Aves > Neognathae > Charadriiformes > Charadriidae > Pluvianellus

Accessions

  • Primary accession
    A0A7L3CQC5

Proteomes

Subcellular Location

Lysosome membrane
; Peripheral membrane protein

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain85-165Glycosyl hydrolase family 30 TIM-barrel

Sequence similarities

Belongs to the glycosyl hydrolase 30 family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Fragment
  • Length
    165
  • Mass (Da)
    18,077
  • Last updated
    2021-04-07 v1
  • Checksum
    E19501AC67129225
LSPPAAGGRPCDAKDFGHGSLVCACSATYCDTLDPVVLPAPGTYVKYESSKAGKRLERSEGSFQRNAETPDFHLTLDTAQRYQKVKGFGGSVTDSAAINIQSLSKGAQDNLLRSYFSEEGIEYNLVRVPMASTDFSVRLYTYADAEGDFELKHFNLTEEDTRMKV

Features

Showing features for non-terminal residue.

TypeIDPosition(s)Description
Non-terminal residue1
Non-terminal residue165

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
VZTS01000073
EMBL· GenBank· DDBJ
NXT45489.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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