A0A7K7VVC1 · A0A7K7VVC1_9AVES

  • Protein
    Alanine--glyoxylate aminotransferase 2, mitochondrial
  • Gene
    Agxt2
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    5/5

Function

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

  • (2S)-2-aminobutanoate + glyoxylate = 2-oxobutanoate + glycine
  • (R)-3-amino-2-methylpropanoate + pyruvate = 2-methyl-3-oxopropanoate + L-alanine
    This reaction proceeds in the forward direction.
    EC:2.6.1.40 (UniProtKB | ENZYME | Rhea)
  • 2-oxobutanoate + L-alanine = (2S)-2-aminobutanoate + pyruvate
    EC:2.6.1.44 (UniProtKB | ENZYME | Rhea)
  • 2-oxobutanoate + N(omega),N(omega)-dimethyl-L-arginine = (2S)-2-aminobutanoate + 5-(3,3-dimethylguanidino)-2-oxopentanoate
  • 2-oxohexanoate + N(omega),N(omega)-dimethyl-L-arginine = 5-(3,3-dimethylguanidino)-2-oxopentanoate + L-2-aminohexanoate
  • 2-oxopentanoate + N(omega),N(omega)-dimethyl-L-arginine = 5-(3,3-dimethylguanidino)-2-oxopentanoate + L-2-aminopentanoate
  • 3-oxopropanoate + L-alanine = beta-alanine + pyruvate
    This reaction proceeds in the backward direction.
    EC:2.6.1.18 (UniProtKB | ENZYME | Rhea)
  • L-alanine + oxaloacetate = L-aspartate + pyruvate
  • L-ornithine + pyruvate = 5-amino-2-oxopentanoate + L-alanine
  • N(omega),N('omega)-dimethyl-L-arginine + pyruvate = 5-(3,3'-dimethylguanidino)-2-oxopentanoate + L-alanine
  • N(omega),N(omega)-dimethyl-L-arginine + oxaloacetate = 5-(3,3-dimethylguanidino)-2-oxopentanoate + L-aspartate
  • N(omega),N(omega)-dimethyl-L-arginine + pyruvate = 5-(3,3-dimethylguanidino)-2-oxopentanoate + L-alanine
  • N(omega)-methyl-L-arginine + pyruvate = 5-(3-methylguanidino)-2-oxopentanoate + L-alanine
  • glyoxylate + L-alanine = glycine + pyruvate
    This reaction proceeds in the forward direction.
    EC:2.6.1.44 (UniProtKB | ENZYME | Rhea)
  • glyoxylate + L-ornithine = 5-amino-2-oxopentanoate + glycine
  • glyoxylate + N(omega),N('omega)-dimethyl-L-arginine = 5-(3,3'-dimethylguanidino)-2-oxopentanoate + glycine
  • glyoxylate + N(omega),N(omega)-dimethyl-L-arginine = 5-(3,3-dimethylguanidino)-2-oxopentanoate + glycine
  • glyoxylate + N(omega)-methyl-L-arginine = 5-(3-methylguanidino)-2-oxopentanoate + glycine

Cofactor

pyridoxal 5'-phosphate (UniProtKB | Rhea| CHEBI:597326 )

GO annotations

AspectTerm
Molecular Functionpyridoxal phosphate binding
Molecular Functiontransaminase activity

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Alanine--glyoxylate aminotransferase 2, mitochondrial
  • EC number
  • Alternative names
    • (R)-3-amino-2-methylpropionate--pyruvate transaminase
    • Beta-ALAAT II
    • Beta-alanine-pyruvate aminotransferase
    • D-3-aminoisobutyrate-pyruvate aminotransferase
    • D-AIBAT
    • D-beta-aminoisobutyrate-pyruvate aminotransferase

Gene names

    • Name
      Agxt2
    • ORF names
      NOTJUL_R03092

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • B10K-MSB-01
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Archelosauria > Archosauria > Dinosauria > Saurischia > Theropoda > Coelurosauria > Aves > Palaeognathae > Tinamiformes > Tinamidae > Nothocercus

Accessions

  • Primary accession
    A0A7K7VVC1

Proteomes

Family & Domains

Sequence similarities

Family and domain databases

Sequence

  • Sequence status
    Fragment
  • Length
    477
  • Mass (Da)
    53,191
  • Last updated
    2021-04-07 v1
  • Checksum
    2F6974457569486C
QKWKSSVSLQAEMPPCDFVPEKYQSYTYNQMLKIRERNLSPTLLMVYKKPLLLHQGHMQWLFDYEGRRYLDLFAGIATVSVGHCHPKVTAAAQKQLARLWHTSSIYMHPAIQEYAQKLTSLFPDPLKVVFLTNSGSEANDLAMFLARLYTRSFDIICFRGAYHGGSPYTLGVTSVGYYKHGFTSGFGCTTTMLPDVFRGPWGGSHCRDSPVQTIRKCSCSEGVCNAKDQYIEQFKETMNTSVPKTIAGFIVEPIQGVNGTVQYPKGFLKEAFQLVRERGGLCISDEVQTGFGRTGSHFWGFQTHDVLPDIVTMAKGIGNGFPMAAVVTTKEIASALAQNLHFNTFGGNPVACVVGAAVLDAFEEDGLQQNSEEVGTYMLLELAKLRDKFEIVGDVRGKGLMIGIEMVTNKDTCHPLPAEEFSQIWEDCKDMGVLLGRGGLYRQTFRIKPPMCITKKDADFAVEVFRTALERHMERAA

Features

Showing features for non-terminal residue.

TypeIDPosition(s)Description
Non-terminal residue1
Non-terminal residue477

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
VZSV01000003
EMBL· GenBank· DDBJ
NXA44958.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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