A0A7K6ZCM6 · A0A7K6ZCM6_9AVES
- Proteinnon-specific serine/threonine protein kinase
- GeneRock2
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids1397 (go to sequence)
- Protein existenceInferred from homology
- Annotation score4/5
Function
Catalytic activity
- ATP + L-seryl-[protein] = ADP + H+ + O-phospho-L-seryl-[protein]
Cofactor
Features
Showing features for binding site, active site.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Cellular Component | cytoskeleton | |
Cellular Component | nucleus | |
Cellular Component | plasma membrane | |
Molecular Function | ATP binding | |
Molecular Function | metal ion binding | |
Molecular Function | protein serine/threonine kinase activity | |
Molecular Function | small GTPase binding | |
Biological Process | actin cytoskeleton organization | |
Biological Process | positive regulation of centrosome duplication | |
Biological Process | regulation of actin cytoskeleton organization | |
Biological Process | Rho protein signal transduction | |
Biological Process | rhythmic process | |
Biological Process | smooth muscle contraction |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namenon-specific serine/threonine protein kinase
- EC number
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Archelosauria > Archosauria > Dinosauria > Saurischia > Theropoda > Coelurosauria > Aves > Palaeognathae > Tinamiformes > Tinamidae > Nothoprocta
Accessions
- Primary accessionA0A7K6ZCM6
Proteomes
PTM/Processing
Keywords
- PTM
Structure
Family & Domains
Features
Showing features for domain, region, coiled coil, compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 48-310 | Protein kinase | ||||
Sequence: YDVVKVIGRGAFGEVQLVRHKMTQKVYAMKLLSKFEMIKRSDSAFFWEERDIMAFANSPWVVQLFCAFQDDRYLYMVMEYMPGGDLVNLMSNYDVPEKWAKFYTAEVVLALDAIHSMGLIHRDVKPDNMLLDKHGHLKLADFGTCMKMDETGMVRCDTAVGTPDYISPEVLKSQGGDGYYGRECDWWSVGVFLFEMLVGDTPFYADSLVGTYSKIMDHKNSLHFPDDVEISKHAKNLICAFLTDRDVRLGRNGVEEIKHHPFF | ||||||
Domain | 313-381 | AGC-kinase C-terminal | ||||
Sequence: DQWNWDNIRETAAPVVPELSSDIDSSNFDDIEDDKGDVETFPIPKAFVGNQLPFIGFTYYRDNLLLSDS | ||||||
Domain | 450-526 | REM-1 | ||||
Sequence: AVRQLEREKALLQHKNTEYQRKAEHEADKKRNLENEVNSLKDQLEDLKKRNQNSQISNEKINQLQRQLDESNSLLRS | ||||||
Region | 462-484 | Disordered | ||||
Sequence: QHKNTEYQRKAEHEADKKRNLEN | ||||||
Region | 520-543 | Disordered | ||||
Sequence: SNSLLRSESDTAARLRKNQTESTK | ||||||
Coiled coil | 594-972 | |||||
Sequence: ISDLQGRISSLEEEVKNGKSALAKLEMEKRQLQEKLTDLEKEKSNMEIDMTYKFKVMQQNLEQEEAEHKATKARLADKNKIYESIEEAKSEAMKEMEKKLLEERALKQKVENRLLEAEKQRSMLDCDLKQSQQKINELLKQKDKLNEDVKNLTLKIEQETQKRCLTQNDLKMQTQQVNTLKMSEKQLKQENNHLQEIKSSLEKQNNELRKERQDADGQMKELQDQLEAEQYFSTLYKTQVRELKEECEEKTKLCKEMQQKIQELQDERDSLAAQLEITLTKADSEQLARSIAEEQYSDLEKEKIMKELEIKEMMARHKQELTEKDATIASLEEANRTLTSDVANLANEKEELNNKLKEVQEQITKLKEEEANIGNIKAQ | ||||||
Domain | 932-1000 | RhoBD | ||||
Sequence: TSDVANLANEKEELNNKLKEVQEQITKLKEEEANIGNIKAQFEKQLLNERTLKTQAVNKLAEIMNRKGP | ||||||
Coiled coil | 1009-1054 | |||||
Sequence: VRRKEKENRKLHMELKSEREKLTQMMIKYQKEINEMQAQIAEESQI | ||||||
Region | 1127-1159 | Disordered | ||||
Sequence: IATKPSSSRMLLDSDSDSEEESCSQSPSDLDST | ||||||
Domain | 1160-1359 | PH | ||||
Sequence: ESRLEGWLSLPVRNNTKKFGWVKKYVIVSSKKILFYDSEQDKEQSNPYMVLDIDKLFHVRPVTQTDVYRADSKEIPRIFQILYANEGESKKEQEFPVEPMGEKSNYICHKGHEFIPTLYHFPTNCEACMKPLWHMFKPPPALECRRCHIKCHKDHMDKKEEIIAPCKVYYDISTAKNLLLLANSTEEQQKWVSRLVKKIP | ||||||
Domain | 1270-1325 | Phorbol-ester/DAG-type | ||||
Sequence: GHEFIPTLYHFPTNCEACMKPLWHMFKPPPALECRRCHIKCHKDHMDKKEEIIAPC | ||||||
Region | 1355-1397 | Disordered | ||||
Sequence: VKKIPKKPPAPDPFARSSPRTSMKVQPNQSIRRPSRQLPPNKP | ||||||
Compositional bias | 1373-1390 | Polar residues | ||||
Sequence: PRTSMKVQPNQSIRRPSR |
Sequence similarities
Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusFragment
- Length1,397
- Mass (Da)162,331
- Last updated2021-04-07 v1
- Checksum77655B5ED5B5C9E4
Features
Showing features for non-terminal residue, compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Non-terminal residue | 1 | |||||
Sequence: S | ||||||
Compositional bias | 1373-1390 | Polar residues | ||||
Sequence: PRTSMKVQPNQSIRRPSR | ||||||
Non-terminal residue | 1397 | |||||
Sequence: P |