A0A7K6XY86 · A0A7K6XY86_9PASE
- ProteinMyotubularin
- GeneMtm1
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids603 (go to sequence)
- Protein existenceInferred from homology
- Annotation score4/5
Function
Catalytic activity
- 1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-phosphate) + H2O = 1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol-5-phosphate) + phosphate
- 1,2-dioctanoyl-sn-glycero-3-phospho-(1-D-myo-inositol-3-phosphate) + H2O = 1,2-dioctanoyl-sn-glycero-3-phospho-(1D-myo-inositol) + phosphate
- 1,2-dioctanoyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-bisphosphate) + H2O = 1,2-dioctanoyl-sn-glycero-3-phospho-(1D-myo-inositol-5-phosphate) + phosphate
- a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + phosphate
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 313-314 | substrate | |||
Active site | 375 | Phosphocysteine intermediate | |||
Binding site | 375-381 | substrate | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | filopodium | |
Cellular Component | late endosome | |
Cellular Component | plasma membrane | |
Cellular Component | ruffle | |
Cellular Component | sarcomere | |
Molecular Function | phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity | |
Molecular Function | phosphatidylinositol-3-phosphate phosphatase activity | |
Molecular Function | phosphoprotein phosphatase activity | |
Biological Process | mitochondrion distribution | |
Biological Process | muscle cell cellular homeostasis | |
Biological Process | negative regulation of autophagosome assembly | |
Biological Process | phosphatidylinositol dephosphorylation |
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameMyotubularin
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Archelosauria > Archosauria > Dinosauria > Saurischia > Theropoda > Coelurosauria > Aves > Neognathae > Neoaves > Telluraves > Australaves > Passeriformes > Passeroidea > Nectariniidae > Promerops
Accessions
- Primary accessionA0A7K6XY86
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Cell membrane ; Peripheral membrane protein
Keywords
- Cellular component
Structure
Family & Domains
Features
Showing features for compositional bias, region, domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 1-29 | Polar residues | |||
Region | 1-40 | Disordered | |||
Domain | 163-538 | Myotubularin phosphatase | |||
Domain | 344-406 | Tyrosine specific protein phosphatases | |||
Region | 581-603 | Disordered | |||
Sequence similarities
Family and domain databases
Sequence
- Sequence statusFragment
- Length603
- Mass (Da)69,829
- Last updated2021-04-07 v1
- MD5 Checksum44119D0190FCA3B3FEF074420727F008
Features
Showing features for non-terminal residue, compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Non-terminal residue | 1 | ||||
Compositional bias | 1-29 | Polar residues | |||
Non-terminal residue | 603 | ||||
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
VZSE01012186 EMBL· GenBank· DDBJ | NWX64235.1 EMBL· GenBank· DDBJ | Genomic DNA |