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A0A7K6XY86 · A0A7K6XY86_9PASE

Function

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Features

Showing features for binding site, active site.

Type
IDPosition(s)Description
Binding site313-314substrate
Active site375Phosphocysteine intermediate
Binding site375-381substrate

GO annotations

AspectTerm
Cellular Componentfilopodium
Cellular Componentlate endosome
Cellular Componentplasma membrane
Cellular Componentruffle
Cellular Componentsarcomere
Molecular Functionphosphatidylinositol-3,5-bisphosphate 3-phosphatase activity
Molecular Functionphosphatidylinositol-3-phosphate phosphatase activity
Molecular Functionphosphoprotein phosphatase activity
Biological Processmitochondrion distribution
Biological Processmuscle cell cellular homeostasis
Biological Processnegative regulation of autophagosome assembly
Biological Processphosphatidylinositol dephosphorylation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Myotubularin
  • EC number
  • Alternative names
    • Phosphatidylinositol-3,5-bisphosphate 3-phosphatase
    • Phosphatidylinositol-3-phosphate phosphatase

Gene names

    • Name
      Mtm1
    • ORF names
      PROCAF_R11896

Organism names

  • Taxonomic identifier
  • Strain
    • B10K-UC-030-53
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Archelosauria > Archosauria > Dinosauria > Saurischia > Theropoda > Coelurosauria > Aves > Neognathae > Neoaves > Telluraves > Australaves > Passeriformes > Passeroidea > Nectariniidae > Promerops

Accessions

  • Primary accession
    A0A7K6XY86

Proteomes

Subcellular Location

Cell membrane
; Peripheral membrane protein
Cell projection, filopodium
Cell projection, ruffle
Cytoplasm, myofibril, sarcomere
Late endosome

Keywords

Family & Domains

Features

Showing features for compositional bias, region, domain.

Type
IDPosition(s)Description
Compositional bias1-29Polar residues
Region1-40Disordered
Domain163-538Myotubularin phosphatase
Domain344-406Tyrosine specific protein phosphatases
Region581-603Disordered

Sequence similarities

Family and domain databases

Sequence

  • Sequence status
    Fragment
  • Length
    603
  • Mass (Da)
    69,829
  • Last updated
    2021-04-07 v1
  • MD5 Checksum
    44119D0190FCA3B3FEF074420727F008
MASSSTPKYNSNSLENSSSKQTLKDGTNWEQNEEIPRLPGETRVTDKDVIYMCPFNGPVKGRVYITNYRLYLRSVENDPVVILNVPLGVISRIEKMGGASSRGENSYGLDITCKDMRNLRFALKQEGHSRRDIFEVLTKYAFPQSHNLPFFAFVNEEKFSENGWMVYNPMSEYRRQGLPNERWRVTFINEHYGLCDTYPSLLVVPYNATDDDLKKVAAFRSRSRIPVLSWIHPETQAVIMRCSQPLVGMSGKRNKDDERYLDIIREANGQISKLTIYDARPNVNAVANKATGGGYESEDAYPNAELFFLDIHNIHVMRESLKKLKDIVYPNVEESHWLSSLESTHWLEHIKLVLTGAIQVADKVSSGRSSVLVHCSDGWDRTAQLTSLAMLMLDSYYRTIEGFEVLVQKEWISFGHKFSSRIGHGDKNHADADRSPIFLQFIDCVWQMSKQFPTAFEFNEQFLITILDHLYSCRFGTFLYNSEFLREKEKVTEKTLSLWSLINSEKSKYTNPFYSKELNRALYPVASMRHLELWVNYYIRWNPRIRQQQPNPVEQRYMELLALRDDYIRRLEELQITNNSKISNSSASSTSPSQMVSQVQTHF

Features

Showing features for non-terminal residue, compositional bias.

Type
IDPosition(s)Description
Non-terminal residue1
Compositional bias1-29Polar residues
Non-terminal residue603

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
VZSE01012186
EMBL· GenBank· DDBJ
NWX64235.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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