A0A7K6DFL8 · A0A7K6DFL8_9PASS
- ProteinEctonucleoside triphosphate diphosphohydrolase 1
- GeneEntpd1
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids510 (go to sequence)
- Protein existenceInferred from homology
- Annotation score5/5
Function
Catalytic activity
- 2 H2O + ITP = 2 H+ + IMP + 2 phosphateThis reaction proceeds in the forward direction.
- 2 H2O + UTP = 2 H+ + 2 phosphate + UMPThis reaction proceeds in the forward direction.
- ADP + H2O = AMP + H+ + phosphateThis reaction proceeds in the forward direction.
- ATP + 2 H2O = AMP + 2 H+ + 2 phosphateThis reaction proceeds in the forward direction.
- ATP + H2O = ADP + H+ + phosphateThis reaction proceeds in the forward direction.
- CDP + H2O = CMP + H+ + phosphateThis reaction proceeds in the forward direction.
- CTP + 2 H2O = CMP + 2 H+ + 2 phosphateThis reaction proceeds in the forward direction.
- CTP + H2O = CDP + H+ + phosphateThis reaction proceeds in the forward direction.
- GDP + H2O = GMP + H+ + phosphateThis reaction proceeds in the forward direction.
- GTP + 2 H2O = GMP + 2 H+ + 2 phosphateThis reaction proceeds in the forward direction.
- H2O + IDP = H+ + IMP + phosphateThis reaction proceeds in the forward direction.
- H2O + ITP = H+ + IDP + phosphateThis reaction proceeds in the forward direction.
- H2O + UDP = H+ + phosphate + UMPThis reaction proceeds in the forward direction.
- H2O + UTP = H+ + phosphate + UDPThis reaction proceeds in the forward direction.
- a ribonucleoside 5'-diphosphate + H2O = a ribonucleoside 5'-phosphate + H+ + phosphateThis reaction proceeds in the forward direction.
- a ribonucleoside 5'-triphosphate + H2O = a ribonucleoside 5'-diphosphate + H+ + phosphateThis reaction proceeds in the forward direction.
Cofactor
Features
Showing features for active site, binding site.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | membrane | |
Molecular Function | ATP binding | |
Molecular Function | hydrolase activity |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameEctonucleoside triphosphate diphosphohydrolase 1
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Archelosauria > Archosauria > Dinosauria > Saurischia > Theropoda > Coelurosauria > Aves > Neognathae > Passeriformes > Meliphagoidea > Acanthizidae > Origma
Accessions
- Primary accessionA0A7K6DFL8
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 477-499 | Helical | ||||
Sequence: YVGLMVLCSLVLAAVLLFTWLLL |
Keywords
- Cellular component
PTM/Processing
Features
Showing features for signal, chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Signal | 1-25 | |||||
Sequence: TILLILGFLSTLAVIALIAVAVTQN | ||||||
Chain | PRO_5029472838 | 26-510 | Ectonucleoside triphosphate diphosphohydrolase 1 | |||
Sequence: QPLPENIKYGIVLDAGSSHTNLYVYEWPAEKENDTGVVKQVEVCKVQGPGISGYSHATEEAGPSLAKCLQRAKEVIPSAQHKETPVYLGATAGMRLLRLQNESAADKVLSSVEKTLRLAPFNFQGARIITGQEEGAYGWITINYLLGNFKQSGWKKLLHSLKSLSETSGALDLGGASTQITFVSKDLSSESPENQLYFRLYGKDYQVYTHSFLCYGKDQALQQKLARDLQASTSTPALGCWGCKSCWSSSLLDPCFHQGYQRTINISDFFKNPCTSDKKKQLPFNQLYIEGEGDYQKCRENIQKLFNKTSCPYSSCSFNGIYLPPLQGDFGAFSAFYFVMNFLNLTGEQTPPALSTVTSTIESFCARPWQEVKTDYHDIKEKYLSEYCFSGAYILSLLENGYEFTENNWQMIHFLGKIGSSDAGWTLGYMLNLTNMIPAEEPAGPPLSHGSYVGLMVLCSLVLAAVLLFTWLLLHKPKCLQKGIV |
Interaction
Subunit
Homodimer; disulfide-linked.
Structure
Sequence
- Sequence statusFragment
- Length510
- Mass (Da)56,530
- Last updated2021-04-07 v1
- Checksum1FBF6CAB35888674
Features
Showing features for non-terminal residue.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Non-terminal residue | 1 | |||||
Sequence: T | ||||||
Non-terminal residue | 510 | |||||
Sequence: V |
Keywords
- Technical term