A0A7K5N143 · A0A7K5N143_CHRMC

Function

function

Catalyzes the scrambling of phospholipids across the outer mitochondrial membrane; the mechanism is unrelated to channel activity and is capable of translocating both anionic and zwitterionic phospholipids.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

  • ATP(in) = ATP(out)
  • Ca2+(in) = Ca2+(out)
  • Fe(III)-[cytochrome c](out) = Fe(III)-[cytochrome c](in)
  • K+(in) = K+(out)
  • L-glutamate(out) = L-glutamate(in)
  • Mg2+(in) = Mg2+(out)
  • Na+(in) = Na+(out)
  • acetylcholine(in) = acetylcholine(out)
  • chloride(in) = chloride(out)
  • dopamine(out) = dopamine(in)

GO annotations

AspectTerm
Cellular Componentmembrane raft
Cellular Componentmitochondrial outer membrane
Cellular Componentplasma membrane
Cellular Componentpore complex
Molecular Functionporin activity
Molecular Functionvoltage-gated monoatomic anion channel activity
Biological Processapoptotic process

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Non-selective voltage-gated ion channel VDAC1
  • Alternative names
    • Voltage-dependent anion-selective channel protein 1

Gene names

    • Name
      Vdac1
    • ORF names
      CHRMAC_R10358

Organism names

Accessions

  • Primary accession
    A0A7K5N143

Proteomes

Subcellular Location

Cell membrane
; Multi-pass membrane protein
Membrane raft
; Multi-pass membrane protein
Membrane
; Multi-pass membrane protein

Keywords

PTM/Processing

Keywords

Family & Domains

Sequence similarities

Belongs to the eukaryotic mitochondrial porin family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Fragment
  • Length
    285
  • Mass (Da)
    30,891
  • Last updated
    2021-04-07 v1
  • Checksum
    501FF47220D3DDC3
QKMAVPPAYADLGKSARDVFTKGYGFGLIKLDLKTKSENGLEFTSSGSANSETSKVSGSLETKYKWVEYGLMFTEKWNTDNTLGTEITLEDQLARGLKLTFDSSFSPNTGKKSAKVKTGYKRDHINIGCDMDFDIAGPSIRGALVVGYEGWLAGYQMTFETTKSRVTQSNFAVGYKTDEFQLHTNVNDGTEFGGSIYQKVNDKLETAVNLAWTAGNSNTRFGIAAKYQIDPDASFSAKVNNSSLIGLGYTQTLKPGIKLTLSALLDGKNVNAGGHKLGLGLEFEA

Features

Showing features for non-terminal residue.

TypeIDPosition(s)Description
Non-terminal residue1
Non-terminal residue285

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
VYZF01000032
EMBL· GenBank· DDBJ
NWT36203.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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