A0A7K5CRK7 · A0A7K5CRK7_9TYRA

  • Protein
    Myotubularin
  • Gene
    Mtm1
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    4/5

Function

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Features

Showing features for binding site, active site.

TypeIDPosition(s)Description
Binding site313-314substrate
Active site375Phosphocysteine intermediate
Binding site375-381substrate

GO annotations

AspectTerm
Cellular Componentfilopodium
Cellular Componentlate endosome
Cellular Componentplasma membrane
Cellular Componentruffle
Cellular Componentsarcomere
Molecular Functionphosphatidylinositol-3,5-bisphosphate 3-phosphatase activity
Molecular Functionphosphatidylinositol-3-phosphate phosphatase activity
Molecular Functionphosphoprotein phosphatase activity
Biological Processlipid metabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Myotubularin
  • EC number
  • Alternative names
    • Phosphatidylinositol-3,5-bisphosphate 3-phosphatase
    • Phosphatidylinositol-3-phosphate phosphatase

Gene names

    • Name
      Mtm1
    • ORF names
      PACMIN_R13682

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • B10K-DU-001-72
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Archelosauria > Archosauria > Dinosauria > Saurischia > Theropoda > Coelurosauria > Aves > Neognathae > Passeriformes > Tyrannidae > Pachyramphus

Accessions

  • Primary accession
    A0A7K5CRK7

Proteomes

Subcellular Location

Cell membrane
; Peripheral membrane protein
Cell projection, filopodium
Cell projection, ruffle
Cytoplasm, myofibril, sarcomere
Endosome
Late endosome

Keywords

Family & Domains

Features

Showing features for compositional bias, region, domain.

TypeIDPosition(s)Description
Compositional bias1-25Polar residues
Region1-40Disordered
Compositional bias26-40Basic and acidic residues
Domain163-538Myotubularin phosphatase
Domain344-406Tyrosine specific protein phosphatases
Region579-603Disordered

Sequence similarities

Family and domain databases

Sequence

  • Sequence status
    Fragment
  • Length
    603
  • Mass (Da)
    69,751
  • Last updated
    2021-04-07 v1
  • Checksum
    E86520F15E674C58
MASSSTPKYNSNSLESSSSKRTLKDGTNWEQNEEIPRLPGETRVTDKDVIYMCPFNGPVKGRVYITNYRLYLRSVENDPVVVLNVPLGVISRIEKMGGASSRGENSYGLDITCKDMRNLRFALKQEGHSRRDIFEVLTKYAFPQSHNLLFFAFVNEEKFSENGWMVYNPMSEYRRQGLPNDRWRVTFINEHYGLCDTYPSLLVVPYNATDEDLKKVAAFRSRNRIPVLSWIHPETQAVIMRCSQPLVGMSGKRNKDDERYLDIIREANGQISKLTIYDARPNVNAVANKATGGGYEGEDAYPNAELFFLDIHNIHVMRESLKKLKDIVYPNVEESHWLSSLESTHWLEHIKLVLTGAIQVADKVSSGRSSVLVHCSDGWDRTAQLTSLAMLMLDSYYRTIEGFEVLVQKEWISFGHKFASRIGHGDKNHADADRSPIFLQFIDCVWQMSKQFPTAFEFNEQFLITILDHLYSCRFGTFLYNSESVREKEKVAEKTLSLWSLINSEKSKYTNPFYSKELNRALYPVASMRHLELWVNYYIRWNPRIRQQQPNPVEQRYMELLALRDDYIRRLEELQITNNSKIPNSSASSTSPSQMMSQVQTHF

Features

Showing features for non-terminal residue, compositional bias.

TypeIDPosition(s)Description
Non-terminal residue1
Compositional bias1-25Polar residues
Compositional bias26-40Basic and acidic residues
Non-terminal residue603

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
VYXB01000662
EMBL· GenBank· DDBJ
NWS10604.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
FeedbackHelp