A0A7K4GUN9 · A0A7K4GUN9_9ARCH
- ProteinK(+)-insensitive pyrophosphate-energized proton pump
- GenehppA
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids700 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.
Catalytic activity
- diphosphate + H+(in) + H2O = 2 H+(out) + 2 phosphate
Cofactor
Features
Showing features for site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Site | 476 | Determinant of potassium independence | ||||
Sequence: K |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | plasma membrane | |
Molecular Function | diphosphate hydrolysis-driven proton transmembrane transporter activity | |
Molecular Function | inorganic diphosphate phosphatase activity | |
Molecular Function | magnesium ion binding |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameK(+)-insensitive pyrophosphate-energized proton pump
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageArchaea > Asgard group > Candidatus Lokiarchaeota
Accessions
- Primary accessionA0A7K4GUN9
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Cell membrane ; Multi-pass membrane protein
Membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 6-23 | Helical | ||||
Sequence: LLVSLIAGIVSIGMAMYF | ||||||
Transmembrane | 56-74 | Helical | ||||
Sequence: YMVLAVFVGALFFVILFLL | ||||||
Transmembrane | 94-115 | Helical | ||||
Sequence: VAYLIGSVGSMLAGYLGLYVGV | ||||||
Transmembrane | 135-160 | Helical | ||||
Sequence: VAFFGGSVMGLAVVGVALIGVSLLYW | ||||||
Transmembrane | 166-182 | Helical | ||||
Sequence: LVVLGFSFGASSIALFM | ||||||
Transmembrane | 240-260 | Helical | ||||
Sequence: YVASIVASMMLAASLALITNI | ||||||
Transmembrane | 272-294 | Helical | ||||
Sequence: LVVTPVVLCGVGLIASLIGIFII | ||||||
Transmembrane | 306-329 | Helical | ||||
Sequence: LNNGTYYATLIFAGIAAIFTWILT | ||||||
Transmembrane | 341-364 | Helical | ||||
Sequence: WRIYFAVLIGLASGIVMGFTSDYF | ||||||
Transmembrane | 385-407 | Helical | ||||
Sequence: VVILSGFSYGLLSVVPPTLGIIV | ||||||
Transmembrane | 413-436 | Helical | ||||
Sequence: YLLAGVFGVAMAAVGMLAIVGTIV | ||||||
Transmembrane | 481-499 | Helical | ||||
Sequence: GFAIGAANLTVFALLFSFA | ||||||
Transmembrane | 514-536 | Helical | ||||
Sequence: VLIGAFVGVVVPALFSALLVLAV | ||||||
Transmembrane | 589-622 | Helical | ||||
Sequence: ITVPIAIGIIFGVASLGAFLAGAILSGFVFAVFM | ||||||
Transmembrane | 670-691 | Helical | ||||
Sequence: INTLLVVMSLTASIFMGLLLLF |
Keywords
- Cellular component
Interaction
Subunit
Homodimer.
Structure
Family & Domains
Sequence similarities
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length700
- Mass (Da)73,327
- Last updated2021-04-07 v1
- ChecksumEB2BE2CF530E7B24