A0A7K0F5T0 · A0A7K0F5T0_9FLAO
- ProteinType III pantothenate kinase
- GenecoaX
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids244 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
Catalytic activity
- (R)-pantothenate + ATP = (R)-4'-phosphopantothenate + ADP + H+
Cofactor
Protein has several cofactor binding sites:
K+ (UniProtKB | Rhea| CHEBI:29103 )
Note: A monovalent cation. Ammonium or potassium.
Pathway
Cofactor biosynthesis; coenzyme A biosynthesis; CoA from (R)-pantothenate: step 1/5.
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 6-13 | ATP (UniProtKB | ChEBI) | |||
Binding site | 87 | substrate | |||
Binding site | 94-97 | substrate | |||
Active site | 96 | Proton acceptor | |||
Binding site | 117 | K+ (UniProtKB | ChEBI) | |||
Binding site | 120 | ATP (UniProtKB | ChEBI) | |||
Binding site | 172 | substrate | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | ATP binding | |
Molecular Function | metal ion binding | |
Molecular Function | pantothenate kinase activity | |
Biological Process | coenzyme A biosynthetic process | |
Biological Process | phosphorylation |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameType III pantothenate kinase
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Bacteroidota > Flavobacteriia > Flavobacteriales > Flavobacteriaceae > Flavobacterium
Accessions
- Primary accessionA0A7K0F5T0
Proteomes
Subcellular Location
Interaction
Subunit
Homodimer.
Structure
Sequence
- Sequence statusComplete
- Length244
- Mass (Da)27,509
- Last updated2021-04-07 v1
- Checksum92ADB2548F216D09
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
WKKE01000001 EMBL· GenBank· DDBJ | MRX37703.1 EMBL· GenBank· DDBJ | Genomic DNA |