A0A7K0F5T0 · A0A7K0F5T0_9FLAO

Function

function

Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

Protein has several cofactor binding sites:
K+ (UniProtKB | Rhea| CHEBI:29103 )

NH4+ (UniProtKB | Rhea| CHEBI:28938 )

K+ (UniProtKB | Rhea| CHEBI:29103 )

Note: A monovalent cation. Ammonium or potassium.

Pathway

Cofactor biosynthesis; coenzyme A biosynthesis; CoA from (R)-pantothenate: step 1/5.

Features

Showing features for binding site, active site.

Type
IDPosition(s)Description
Binding site6-13ATP (UniProtKB | ChEBI)
Binding site87substrate
Binding site94-97substrate
Active site96Proton acceptor
Binding site117K+ (UniProtKB | ChEBI)
Binding site120ATP (UniProtKB | ChEBI)
Binding site172substrate

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular FunctionATP binding
Molecular Functionmetal ion binding
Molecular Functionpantothenate kinase activity
Biological Processcoenzyme A biosynthetic process
Biological Processphosphorylation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Type III pantothenate kinase
  • EC number
  • Alternative names
    • PanK-III
    • Pantothenic acid kinase

Gene names

    • Name
      coaX
    • ORF names
      GJU43_00305

Organism names

  • Taxonomic identifier
  • Strain
    • LC2016-23
  • Taxonomic lineage
    Bacteria > Bacteroidota > Flavobacteriia > Flavobacteriales > Flavobacteriaceae > Flavobacterium

Accessions

  • Primary accession
    A0A7K0F5T0

Proteomes

Subcellular Location

Keywords

Interaction

Subunit

Homodimer.

Family & Domains

Features

Showing features for coiled coil.

TypeIDPosition(s)Description
Coiled coil23-50

Sequence similarities

Belongs to the type III pantothenate kinase family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    244
  • Mass (Da)
    27,509
  • Last updated
    2021-04-07 v1
  • Checksum
    92ADB2548F216D09
MILTVDVGNTRIKAAVFEGSTVVENFVFEKNELEKKIKKILKKFQNCSDLVVASVGNIEKQSFLAFEKELNIHFLTHEDIFPFTNQYATPKTLGIDRMVLAAGATLQFPKQNRLVIDAGTCITYDFIDEKDNYLGGAISPGLRLRYEALHNFTARLPLLTLESPEHYIGNSTKEAIHSGVVNGFVYEIDGFIDEYRANFSNFIIILTGGDADFLAKRLKNTIFANSNFLLESLSQTFQYKIDND

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
WKKE01000001
EMBL· GenBank· DDBJ
MRX37703.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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