A0A7K0F5N2 · A0A7K0F5N2_9FLAO
- ProteinPutative K(+)-stimulated pyrophosphate-energized sodium pump
- GenehppA
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids849 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na+ movement across the membrane.
Catalytic activity
- Na+(in) + diphosphate + H2O = Na+(out) + 2 phosphate + H+Na+ (in)CHEBI:29101
+ CHEBI:33019 + CHEBI:15377 = Na+ (out)CHEBI:29101+ 2 CHEBI:43474 + CHEBI:15378
Cofactor
Activity regulation
Requires K+ for maximal activity.
Features
Showing features for site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Site | 494 | Determinant of potassium dependence | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | plasma membrane | |
Molecular Function | diphosphate hydrolysis-driven proton transmembrane transporter activity | |
Molecular Function | inorganic diphosphate phosphatase activity | |
Molecular Function | magnesium ion binding | |
Molecular Function | potassium ion binding | |
Biological Process | sodium ion transport |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namePutative K(+)-stimulated pyrophosphate-energized sodium pump
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Bacteroidota > Flavobacteriia > Flavobacteriales > Flavobacteriaceae > Flavobacterium
Accessions
- Primary accessionA0A7K0F5N2
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Cell membrane ; Multi-pass membrane protein
Endomembrane system ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Transmembrane | 6-22 | Helical | |||
Transmembrane | 58-76 | Helical | |||
Transmembrane | 82-103 | Helical | |||
Transmembrane | 134-159 | Helical | |||
Transmembrane | 245-263 | Helical | |||
Transmembrane | 275-299 | Helical | |||
Transmembrane | 319-340 | Helical | |||
Transmembrane | 361-385 | Helical | |||
Transmembrane | 500-519 | Helical | |||
Transmembrane | 531-551 | Helical | |||
Transmembrane | 599-620 | Helical | |||
Transmembrane | 632-649 | Helical | |||
Transmembrane | 705-722 | Helical | |||
Keywords
- Cellular component
Interaction
Subunit
Homodimer.
Structure
Family & Domains
Sequence similarities
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length849
- Mass (Da)88,878
- Last updated2021-04-07 v1
- ChecksumD3942891D58D1A4F
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
WKKE01000001 EMBL· GenBank· DDBJ | MRX37780.1 EMBL· GenBank· DDBJ | Genomic DNA |