A0A7K0F5N2 · A0A7K0F5N2_9FLAO

  • Protein
    Putative K(+)-stimulated pyrophosphate-energized sodium pump
  • Gene
    hppA
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na+ movement across the membrane.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Activity regulation

Requires K+ for maximal activity.

Features

Showing features for site.

TypeIDPosition(s)Description
Site494Determinant of potassium dependence

GO annotations

AspectTerm
Cellular Componentplasma membrane
Molecular Functiondiphosphate hydrolysis-driven proton transmembrane transporter activity
Molecular Functioninorganic diphosphate phosphatase activity
Molecular Functionmagnesium ion binding
Molecular Functionpotassium ion binding
Biological Processsodium ion transport

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Putative K(+)-stimulated pyrophosphate-energized sodium pump
  • EC number
  • Alternative names
    • Membrane-bound sodium-translocating pyrophosphatase
    • Pyrophosphate-energized inorganic pyrophosphatase
      (Na(+)-PPase
      )

Gene names

    • Name
      hppA
    • ORF names
      GJU43_00695

Organism names

  • Taxonomic identifier
  • Strain
    • LC2016-23
  • Taxonomic lineage
    Bacteria > Bacteroidota > Flavobacteriia > Flavobacteriales > Flavobacteriaceae > Flavobacterium

Accessions

  • Primary accession
    A0A7K0F5N2

Proteomes

Subcellular Location

Cell membrane
; Multi-pass membrane protein
Endomembrane system
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane6-22Helical
Transmembrane58-76Helical
Transmembrane82-103Helical
Transmembrane134-159Helical
Transmembrane245-263Helical
Transmembrane275-299Helical
Transmembrane319-340Helical
Transmembrane361-385Helical
Transmembrane500-519Helical
Transmembrane531-551Helical
Transmembrane599-620Helical
Transmembrane632-649Helical
Transmembrane705-722Helical

Keywords

Interaction

Subunit

Homodimer.

Family & Domains

Sequence similarities

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    849
  • Mass (Da)
    88,878
  • Last updated
    2021-04-07 v1
  • Checksum
    D3942891D58D1A4F
MNSFMIYLPIVMAVLGLLFMGIKRSWVLKQDAGDGKMKEISDHIYEGALAFLKAEYRLLTFFVIAASLVLAGISFIVPTTHILIVVAFIFGAFFSALAGNMGMKIATKTNVRTTQAARTSLPQALKVSFGGGTVMGLGVAGLAVLGLTGFFIVFFQIFMNGVWTSSEDMTKVLETLAGFSLGAESIALFARVGGGIYTKAADVGADLVGKVEAGIPEDDPRNPATIADNVGDNVGDVAGMGADLFGSYVATVLAAMVLGNYVIKDMGGNIQDAFGGIGPILLPMAIAGFGILFSIIGTTLVKISDDNAKEAQVQKALNIGNWVSIVLTAIACFFLVRYMLPEVMTMEFFGEGAQQISSMRVFYATLVGLVVGGAISSVTEYYTGLGTKPVMAIVQKSSTGAGTNVIAGLATGMISTFPTVLLFAAAIWISYALAGFYGVALAASAMMATTAMQLAIDAFGPISDNAGGIAEMSELPKEVRTRTDILDSVGNTTAATGKGFAIASAALTSLALFAAYVTFTGIDGINIFKAPVLAMLFVGGMIPVVFSALAMNSVGKAAMDMVYEVRRQFKEIPGIMEGTGKPEYGKCVEISTKAALREMMLPGILTIGFPIAIVLLGKLVYADNNQLIAEMLGGYMAGVTVSGVLWAVFQNNAGGAWDNAKKSFEAGVLINGEMTYKGSDAHKAAVTGDTVGDPFKDTSGPSMNILIKLTCLIGLVIAPILGEGHAASAMAGKASCCAKTEMHAAGDSKCGDLSGMTKEECIKMCKEKGCTAEETAKCLAHYDANGKYVHQKTDCFDTTKYEKNRLEVNLSTVNGVTVGTVTKTENGKTTTEVYEGTEAEVKAKIEAAK

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
WKKE01000001
EMBL· GenBank· DDBJ
MRX37780.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

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