A0A7J8HD89 · A0A7J8HD89_MOLMO
- ProteinU6 snRNA-associated Sm-like protein LSm8
- GeneLSM8
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | precatalytic spliceosome | |
Cellular Component | U4/U6 x U5 tri-snRNP complex | |
Cellular Component | U6 snRNP | |
Molecular Function | RNA binding | |
Biological Process | mRNA splicing, via spliceosome |
Keywords
- Molecular function
- Biological process
Names & Taxonomy
Protein names
- Recommended nameU6 snRNA-associated Sm-like protein LSm8
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Laurasiatheria > Chiroptera > Yangochiroptera > Molossidae > Molossus
Accessions
- Primary accessionA0A7J8HD89
Proteomes
Subcellular Location
Interaction
Subunit
LSm subunits form a heteromer with a doughnut shape.
Structure
Sequence
- Sequence statusComplete
- Length96
- Mass (Da)10,403
- Last updated2021-04-07 v1
- MD5 Checksum897F74829A1B9495A040456B1D44681D
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
JACASF010000007 EMBL· GenBank· DDBJ | KAF6469895.1 EMBL· GenBank· DDBJ | Genomic DNA |