A0A7J7ZYW2 · A0A7J7ZYW2_MYOMY
- ProteinSerine/threonine-protein kinase mTOR
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids2549 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
Catalytic activity
- ATP + L-seryl-[protein] = ADP + H+ + O-phospho-L-seryl-[protein]
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | nucleus | |
Cellular Component | TORC1 complex | |
Cellular Component | TORC2 complex | |
Molecular Function | ATP binding | |
Molecular Function | protein serine/threonine kinase activity | |
Molecular Function | protein-containing complex binding | |
Biological Process | negative regulation of macroautophagy | |
Biological Process | positive regulation of protein metabolic process | |
Biological Process | regulation of cellular component organization | |
Biological Process | TOR signaling |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameSerine/threonine-protein kinase mTOR
- EC number
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Laurasiatheria > Chiroptera > Yangochiroptera > Vespertilionidae > Myotis
Accessions
- Primary accessionA0A7J7ZYW2
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
Structure
Family & Domains
Features
Showing features for domain, region, compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 1382-1982 | FAT | ||||
Sequence: LLGERAAKCRAYAKALHYKELEFQKGPTPAILESLISINNKLQQPEAAAGVLEYAMKHFGELEIQATWYEKLHEWEDALVAYDKKMDTNKDDPELMLGRMRCLEALGEWGQLHQQCCEKWTLVNDETQAKMARMAAAAAWGLGQWDSMEEYTCMIPRDTHDGAFYRAVLALHQDLFSLAQQCIDKARDLLDAELTAMAGESYSRAYGAMVSCHMLSELEEVIQYKLVPERREIIRQIWWERLQGCQRIVEDWQKILMVRSLVVNPHEDMRTWLKYASLCGKSGRLALAHKTLVLLLGVDPSRQLDHPLPTVHPQVTYAYMKNMWKSARKIDAFQHMQHFVQTMQQQAQHAIATEDQQHKQELHKLMARCFLKLGEWQLNLQGINESTIPKVLQYYSAATEHDRSWYKAWHAWAVMNFEAVLHYKHQNQARDEKKKLRHASGANITNTTTASSTAAATTTATSTEGSNSESEAESSENSPTPSPLQKKVAEDLSKTLLMYTVPAVQGFFRSISLSRGNNLQDTLRVLTLWFDYGHWPDVNEALVEGVKAIQIDTWLQVIPQLIARIDTPRPLVGRLIHQLLTDIGRYHPQALIYPLTVASKS | ||||||
Region | 1812-1867 | Disordered | ||||
Sequence: DEKKKLRHASGANITNTTTASSTAAATTTATSTEGSNSESEAESSENSPTPSPLQK | ||||||
Compositional bias | 1821-1865 | Polar residues | ||||
Sequence: SGANITNTTTASSTAAATTTATSTEGSNSESEAESSENSPTPSPL | ||||||
Domain | 2156-2469 | PI3K/PI4K catalytic | ||||
Sequence: IAPSLQVITSKQRPRKLTLMGSNGHEFVFLLKGHEDLRQDERVMQLFGLVNTLLANDPTSLRKNLSIQRYAVIPLSTNSGLIGWVPHCDTLHALIRDYREKKKILLNIEHRIMLRMAPDYDHLTLMQKVEVFEHAVNNTAGDDLAKLLWLKSPSSEVWFDRRTNYTRSLAVMSMVGYILGLGDRHPSNLMLDRLSGKILHIDFGDCFEVAMTREKFPEKIPFRLTRMLTNAMEVTGLDGNYRITCHTVMEVLREHKDSVMAVLEAFVYDPLLNWRLMDTNTKGNKRSRTRTDSYSAGQSVEILNGVELGEPAHK | ||||||
Domain | 2517-2549 | FATC | ||||
Sequence: DTLDVPTQVELLIKQATSHENLCQCYIGWCPFW |
Sequence similarities
Belongs to the PI3/PI4-kinase family.
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length2,549
- Mass (Da)288,902
- Last updated2021-04-07 v1
- Checksum7D2E97A51955649A
Computationally mapped potential isoform sequences
There are 3 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
A0A7J7ZZ88 | A0A7J7ZZ88_MYOMY | mMyoMyo1_013466 | 2583 | ||
A0A7J7ZYV4 | A0A7J7ZYV4_MYOMY | mMyoMyo1_013466 | 2553 | ||
A0A7J8A0D6 | A0A7J8A0D6_MYOMY | mMyoMyo1_013466 | 2001 |
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 1821-1865 | Polar residues | ||||
Sequence: SGANITNTTTASSTAAATTTATSTEGSNSESEAESSENSPTPSPL |
Keywords
- Technical term