A0A7J7R4U9 · A0A7J7R4U9_MYOMY
- ProteinSerine/threonine-protein kinase
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids1053 (go to sequence)
- Protein existenceInferred from homology
- Annotation score4/5
Function
function
Serine/threonine-protein kinase involved in autophagy in response to starvation.
Catalytic activity
- L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H+
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 46 | ATP (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | autophagosome | |
Cellular Component | cytosol | |
Cellular Component | phagophore assembly site membrane | |
Molecular Function | ATP binding | |
Molecular Function | histone H2AS1 kinase activity | |
Biological Process | autophagosome assembly | |
Biological Process | autophagy of mitochondrion | |
Biological Process | axon extension | |
Biological Process | negative regulation of collateral sprouting | |
Biological Process | peptidyl-serine phosphorylation | |
Biological Process | piecemeal microautophagy of the nucleus | |
Biological Process | positive regulation of autophagy | |
Biological Process | protein autophosphorylation | |
Biological Process | response to starvation | |
Biological Process | reticulophagy | |
Biological Process | signal transduction |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameSerine/threonine-protein kinase
- EC number
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Laurasiatheria > Chiroptera > Yangochiroptera > Vespertilionidae > Myotis
Accessions
- Primary accessionA0A7J7R4U9
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
Structure
Family & Domains
Features
Showing features for domain, region, compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 16-278 | Protein kinase | |||
Region | 283-359 | Disordered | |||
Compositional bias | 296-334 | Polar residues | |||
Region | 394-433 | Disordered | |||
Compositional bias | 450-476 | Polar residues | |||
Region | 450-559 | Disordered | |||
Region | 573-613 | Disordered | |||
Region | 711-774 | Disordered | |||
Compositional bias | 752-766 | Polar residues | |||
Sequence similarities
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. APG1/unc-51/ULK1 subfamily.
Family and domain databases
Sequence
- Sequence statusComplete
- Length1,053
- Mass (Da)112,382
- Last updated2021-04-07 v1
- Checksum6EBE69FCCAB5DFEE
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 296-334 | Polar residues | |||
Compositional bias | 450-476 | Polar residues | |||
Compositional bias | 752-766 | Polar residues | |||
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
JABWUV010000037 EMBL· GenBank· DDBJ | KAF6271159.1 EMBL· GenBank· DDBJ | Genomic DNA |