A0A7J7FJA9 · A0A7J7FJA9_DICBM
- ProteinHistone acetyltransferase
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids555 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
Catalytic activity
- L-lysyl-[histone] + acetyl-CoA = N6-acetyl-L-lysyl-[histone] + CoA + H+This reaction proceeds in the forward direction.
Features
Showing features for active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Active site | 445 | Proton donor/acceptor | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | MSL complex | |
Cellular Component | nucleus | |
Molecular Function | histone H4K16 acetyltransferase activity | |
Molecular Function | transcription coregulator activity | |
Biological Process | DNA repair | |
Biological Process | negative regulation of DNA-templated transcription | |
Biological Process | positive regulation of transcription by RNA polymerase II |
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameHistone acetyltransferase
- EC number
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Laurasiatheria > Perissodactyla > Rhinocerotidae > Diceros
Accessions
- Primary accessionA0A7J7FJA9
Proteomes
Subcellular Location
PTM/Processing
Keywords
- PTM
Structure
Family & Domains
Features
Showing features for region, compositional bias, domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Region | 1-36 | Disordered | |||
Region | 103-129 | Disordered | |||
Region | 164-260 | Disordered | |||
Compositional bias | 202-216 | Polar residues | |||
Domain | 269-546 | MYST-type HAT | |||
Sequence similarities
Belongs to the MYST (SAS/MOZ) family.
Family and domain databases
Sequence
- Sequence statusComplete
- Length555
- Mass (Da)62,929
- Last updated2021-04-07 v1
- Checksum59003720BC3DC3BD
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 202-216 | Polar residues | |||
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
JACDTQ010000423 EMBL· GenBank· DDBJ | KAF5928165.1 EMBL· GenBank· DDBJ | Genomic DNA |