A0A7J7FFV4 · A0A7J7FFV4_DICBM

Function

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Features

Showing features for binding site, active site.

112421002003004005006007008009001,0001,1001,200
TypeIDPosition(s)Description
Binding site727-734ATP (UniProtKB | ChEBI)
Binding site754ATP (UniProtKB | ChEBI)
Active site914Proton acceptor
Binding site918ATP (UniProtKB | ChEBI)
Binding site919Mg2+ (UniProtKB | ChEBI)
Binding site932Mg2+ (UniProtKB | ChEBI)

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentearly endosome
Cellular Componentendoplasmic reticulum
Cellular Componentplasma membrane
Cellular Componentreceptor complex
Molecular FunctionATP binding
Molecular Functiongrowth factor binding
Molecular Functionmetal ion binding
Molecular Functionvascular endothelial growth factor receptor activity
Biological Processangiogenesis
Biological Processcell migration
Biological Processendothelial cell differentiation
Biological Processpositive regulation of angiogenesis
Biological Processpositive regulation of cell migration
Biological Processregulation of MAPK cascade
Biological Processvascular endothelial growth factor receptor signaling pathway

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Vascular endothelial growth factor receptor 2
  • EC number

Gene names

    • ORF names
      HPG69_001520

Organism names

Accessions

  • Primary accession
    A0A7J7FFV4

Proteomes

Subcellular Location

Cell membrane
; Single-pass type I membrane protein
Cytoplasmic vesicle
Early endosome
Endoplasmic reticulum
Endosome
Membrane
; Single-pass type I membrane protein
Vesicle

Keywords

PTM/Processing

Features

Showing features for signal, chain.

TypeIDPosition(s)Description
Signal1-19
ChainPRO_502945820120-1242Vascular endothelial growth factor receptor 2

Keywords

Family & Domains

Features

Showing features for domain, region, compositional bias.

TypeIDPosition(s)Description
Domain224-323Ig-like
Domain328-414Ig-like
Domain421-544Ig-like
Domain553-625Ig-like
Domain720-1048Protein kinase
Region1166-1242Disordered
Compositional bias1172-1201Polar residues
Compositional bias1223-1242Polar residues

Sequence similarities

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    1,242
  • Mass (Da)
    138,520
  • Last updated
    2021-04-07 v1
  • Checksum
    C3D79963769741A3
MEGKALLAIALWLCVETRAASVGLSSVSVDPPRLSIQKDILTIMANTTLQITCRGERDLDWLWPNNQSGSENRVGVTECSDGFFCKTLTIPEVIGNDTGAYKCFYRDTDTASVVYVYVQDYRSPFIASVSDQHGVVYITENKNKTVVIPCLGSISNLNVSLCARYPEKRFVPDGNRISWDSKKGFTIPSYMISYAGMVFCEAKINDETYQSIMYIVVVVGYKIYDVVLSPPDGIELSVGEKLVLNCTARTELNVGIDFNWEYPSLKHQHKKLVNRDLKTQSGSEMKKFLSTLTIDRVTRSDRGQYTCAASSGLMTKRNSTLVTVHEKPFVAFGSGMESLVEVTVGDHVKVPVKYLGYPPPEIKWYKNGRPIESNHTIKVGHALTIMEVSEKDAGNYTIILTNPISKEKQSHVVSLVVNVPPQIGEKSLISPVDSYQYGTTQVLTCTVYAVPPPLHIRWYWQLEEECTYKPTQAVLMTNPYTCKEWRNMEDFQGGNKIEVNKNQFALIEGKNKTVSTLVIQVANVSALYKCEAVNKAGRGERVISFHVTKRMAPMITGNLENQTTSIGETIEVACTVSGNPSPQITWFKDNETLVEDSGIVLKDGNRNLTIRRVRKEDEGLYTCQACSVLGCAKVEAFFIVEGAQEKTNLEVIILVGTAVIAMFFWLLLVIVLRTVKRANGGELKTGYLSIVMDPDELPLDEHCERLPYDASKWEFPRDRLKLGKPLGRGAFGQVIEADAFGIDKTATCKTVAVKMLKEGATHSEHRALMSELKILIHIGHHLNVVNLLGACTKPGGPLMVIVEFCKFGNLSTYLRSKRNEFVPYKSKGARFRPGKEYVGEITVDPKRRLDSITSSQSSASSGFVEEKSLSDVEEEEVSEDLYKNFLTLEHLICYSFQVAKGMEFLASRKCIHRDLAARNILLSEKNVVKICDFGLARDIYKDPDYVRKGDARLPLKWMAPETIFDRVYTIQSDVWSFGVLLWEIFSLGASPYPGVKIDEEFCRRLKEGTRMRAPDYTTPEMYQTMLDCWHGEPSQRPTFSELVEHLGNLLQANAQQDGKDYIVLPISETLSMEEDSGLSLPTSPVSCMEEEEVCDPKFHYDNTAGISQYLQNSKRKSRPVSVKTFEDIPLEEPEVKVIPDDNQTDSGMVLASEELKTLEDRTKLAPSFSGLMPSKSKESVASEGSNQTSGYQSGYHSDDTDTTVYSSEEAELLKLMEMGQQAGSAAQILQPGSGTTLSSPPV

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias1172-1201Polar residues
Compositional bias1223-1242Polar residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JACDTQ010000745
EMBL· GenBank· DDBJ
KAF5926889.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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