A0A7J7FER0 · A0A7J7FER0_DICBM

Function

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Features

Showing features for binding site, active site, site.

1969100200300400500600700800900
TypeIDPosition(s)Description
Binding site131-133(6R)-10-formyltetrahydrofolate (UniProtKB | ChEBI)
Active site149Proton donor
Binding site185(6R)-10-formyltetrahydrofolate (UniProtKB | ChEBI)
Site185Essential for catalytic activity
Binding site613-615NADP+ (UniProtKB | ChEBI)
Binding site639-642NADP+ (UniProtKB | ChEBI)
Binding site672-677NADP+ (UniProtKB | ChEBI)
Binding site692-693NADP+ (UniProtKB | ChEBI)
Active site715
Active site715Proton acceptor
Active site749Proton donor
Binding site799NADP+ (UniProtKB | ChEBI)
Binding site846-848NADP+ (UniProtKB | ChEBI)

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcytoplasm
Molecular Functionaldehyde dehydrogenase (NAD+) activity
Molecular Functionformyltetrahydrofolate dehydrogenase activity
Biological Process10-formyltetrahydrofolate catabolic process
Biological Processbiosynthetic process
Biological Processone-carbon metabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    formyltetrahydrofolate dehydrogenase
  • EC number

Gene names

    • ORF names
      HPG69_001136

Organism names

Accessions

  • Primary accession
    A0A7J7FER0

Proteomes

Subcellular Location

PTM/Processing

Keywords

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain360-437Carrier

Sequence similarities

Belongs to the aldehyde dehydrogenase family.
In the C-terminal section; belongs to the aldehyde dehydrogenase family. ALDH1L subfamily.
In the N-terminal section; belongs to the GART family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    969
  • Mass (Da)
    107,352
  • Last updated
    2021-04-07 v1
  • Checksum
    296E556B47F61D16
MLRRGSQALRRFSTGRNVYYPYVFHPCQHLSSLIISQVYFKNKLKVALIGQSLFGQEVYSHLCKEGHRVVGVFTVPDKDGKADPLALAAEKDGTPVFKFPRWRMKGKTIKEVADAYRSVGAELNVLPFCTQFIPMDVIDSPKHGSIIYHPSILPRHRGASAINWTLIMGDKKAGFSVFWADDGLDTGPILLQRSCDVKPNDTVDALYNRFLYPEGIKAMVEAVQLIADGKAPRIPQPEEGATYEGIQKKENAEISWDQSAEVLHNWIRGHDKVPGAWTEINGQMVTFYGSSLLNSSVPPGEPLEIKGAKKPGLVTKNGLVLFGNDGKALMVRNLQFEDGKMIPASQYFSAGETSVVELTAEELKVAETIKVIWAGILSNIPVIENSTDFFKSGARSMDVVRLVEEIRQKCGGLQLQNEDVYMATKFEDFIQKVVRKLRGEDQEAELVVDYVSKEVNQMTVKMPYQCFINGEFTDADDGKTYDTINPTDGSTICKVSYASLADVDKAVAAAKDAFENGEWGRMNARDRGRLMYRLADLLEENQEELATIEALDSGAVYTLALKTHIGMSVQTFRYFAGWCDKIQGSTIPINQARPNRNLTFTKKEPLGVCAIIIPWNYPLMMLAWKSAACLAAGNTLVLKPAQVTPLTALKFAELSVKAGFPKGVINIIPGSGGIAGQRLSEHPDIRKLGFTGSTLIGKQIMKSCAVSNLKKVSLELGGKSPLIIFNDCELDNAVRMGMGAVFFNKGENCIAAGRLFVEESIHDEFVTRVVEEIKKMKIGDPLDRSTDHGPQNHKAHLEKLLQYCETGVKEGATLVYGGRQVQRPGFFMEPTVFTDVEDHMYLAKEESFGPIMVISKFQNGDIDGVLQRANNTEYGLASGVFTRDINKAMYVSEKLEAGTVFINTYNKTDVAAPFGGVKQSGFGKDLGKLYFFHCVFPLSHIREKSAVFHAPREEALNEYLKTKTVTLEY

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JACDTQ010000745
EMBL· GenBank· DDBJ
KAF5926509.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
FeedbackHelp