A0A7J7FDT6 · A0A7J7FDT6_DICBM
- ProteinTubulin--tyrosine ligase
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids377 (go to sequence)
- Protein existencePredicted
- Annotation score2/5
Function
function
Catalyzes the post-translational addition of a tyrosine to the C-terminal end of detyrosinated alpha-tubulin.
Catalytic activity
- ATP + C-terminal L-alpha-aminoacyl-L-glutamyl-L-glutamyl-[tubulin] + L-tyrosine = ADP + C-terminal L-alpha-aminoacyl-L-glutamyl-L-glutamyl-L-tyrosyl-[tubulin] + H+ + phosphate
Cofactor
Protein has several cofactor binding sites:
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | spindle microtubule | |
Molecular Function | tubulin-tyrosine ligase activity | |
Biological Process | microtubule cytoskeleton organization | |
Biological Process | protein modification process |
Keywords
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameTubulin--tyrosine ligase
- EC number
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Laurasiatheria > Perissodactyla > Rhinocerotidae > Diceros
Accessions
- Primary accessionA0A7J7FDT6
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Interaction
Subunit
Monomer.
Structure
Sequence
- Sequence statusComplete
- Length377
- Mass (Da)43,276
- Last updated2021-04-07 v1
- Checksum0057D3BC1833C8A4
Keywords
- Technical term