A0A7J7FC18 · A0A7J7FC18_DICBM

Function

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

FAD (UniProtKB | Rhea| CHEBI:57692 )

Pathway

Amino-acid degradation; L-leucine degradation; (S)-3-hydroxy-3-methylglutaryl-CoA from 3-isovaleryl-CoA: step 1/3.

Features

Showing features for binding site, active site.

TypeIDPosition(s)Description
Binding site198-207FAD (UniProtKB | ChEBI)
Binding site207substrate
Binding site231-233FAD (UniProtKB | ChEBI)
Binding site255-256substrate
Binding site310substrate
Binding site317-320substrate
Active site319Proton acceptor
Binding site345FAD (UniProtKB | ChEBI)
Binding site356FAD (UniProtKB | ChEBI)
Binding site413-417FAD (UniProtKB | ChEBI)
Binding site440-441substrate
Binding site442-444FAD (UniProtKB | ChEBI)

GO annotations

AspectTerm
Molecular Functionflavin adenine dinucleotide binding
Molecular Functionisovaleryl-CoA dehydrogenase activity
Biological ProcessL-leucine catabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Isovaleryl-CoA dehydrogenase, mitochondrial
  • EC number
  • Alternative names
    • Butyryl-CoA dehydrogenase

Gene names

    • ORF names
      HPG69_002007

Organism names

Accessions

  • Primary accession
    A0A7J7FC18

Proteomes

PTM/Processing

Keywords

Family & Domains

Features

Showing features for domain, region.

TypeIDPosition(s)Description
Domain46-79Acyl-CoA dehydrogenase/oxidase N-terminal
Region75-94Disordered
Domain106-193Acyl-CoA dehydrogenase/oxidase N-terminal
Domain197-294Acyl-CoA oxidase/dehydrogenase middle
Domain307-453Acyl-CoA dehydrogenase/oxidase C-terminal

Sequence similarities

Belongs to the acyl-CoA dehydrogenase family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    459
  • Mass (Da)
    49,700
  • Last updated
    2021-04-07 v1
  • Checksum
    81D8C51E55CD2511
MATVARLLGRRVVSWRLRPPLPPLAGVVSQRAHSLLPVDDAINGLSEEQKQLRQTVAKFLQDHLAPHAQEIDHSNEFKNLRVSHEAHTGGTGGQSGSWAGSCAAAAWKGSHSLLEFWKQLGKLGVLGITAPVQYGGSGLGYLEHVLVMEEISRASGAVGLSYGTHSNLCLNQIVRNGNEAQKEKYLPKLISGEYIGALAMSESNAGSDVVSMKLKAEKKGDHYILNGNKFWITNGPDADILIVYAKTDLAAVPASRGITAFIVEKDMPGFSTSKKLDKLGMRGSNTCELIFEDCKVPATNILGHPSKGVYVLMSGLDLERLVLAGGPLGLMQAVLDHTIPYLHMREAFGQKIGHFQLMQGKMADMYTRLMACRQYVYNVAKACDEGHCTSKDCAAVILYSAECATQVALDGIQCFGGNGXXXDFPMGRFLRDAKLYEIGAGTSEVRRLVIGRAFNADFQ

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JACDTQ010000812
EMBL· GenBank· DDBJ
KAF5925560.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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