A0A7J7F7B0 · A0A7J7F7B0_DICBM

Function

function

Mediates the post-translational oxidative deamination of lysine residues on target proteins leading to the formation of deaminated lysine (allysine).

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

Cu cation (UniProtKB | Rhea| CHEBI:23378 )

GO annotations

AspectTerm
Cellular Componentbasement membrane
Cellular Componentchromosome
Cellular Componentendoplasmic reticulum
Cellular Componentextracellular space
Cellular Componentmembrane
Cellular Componentnucleus
Molecular Functioncopper ion binding
Molecular Functionprotein-lysine 6-oxidase activity
Biological Processchromatin organization
Biological Processcollagen fibril organization
Biological Processpeptidyl-lysine oxidation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Lysyl oxidase homolog
  • EC number

Gene names

    • ORF names
      HPG69_006727

Organism names

Accessions

  • Primary accession
    A0A7J7F7B0

Proteomes

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for signal, chain, disulfide bond.

Type
IDPosition(s)Description
Signal1-25
ChainPRO_502979862826-813Lysyl oxidase homolog
Disulfide bond83↔147
Disulfide bond127↔137
Disulfide bond240↔250
Disulfide bond370↔380
Disulfide bond486↔496

Post-translational modification

The lysine tyrosylquinone cross-link (LTQ) is generated by condensation of the epsilon-amino group of a lysine with a topaquinone produced by oxidation of tyrosine.

Keywords

Interaction

Subunit

Component of some chromatin repressor complex. Interacts with SNAI1. Interacts with TAF10. Interacts with HSPA5. Interacts with EFEMP2.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain57-152SRCR
Domain163-277SRCR
Domain301-400SRCR
Domain410-519SRCR

Sequence similarities

Belongs to the lysyl oxidase family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    813
  • Mass (Da)
    90,656
  • Last updated
    2021-04-07 v1
  • Checksum
    DAE24C3A86A163CE
MERRGGSCFGSCLAVLCLLPSLSLAQYEGWPHYPEYFQQPAPEYHQPQATSDVKIQLRLAGQKRKHNEGRVEVYYDGKWGTVCDDDFSIHAAHVVCRELGYVEAKSWTASSSYGKGEGPIWLDNIYCTGQETTLAACSSNGWGVTDCKHTEDNLNTQVEDIRIRAILSTYRKRKPVTEGYVEVKEGKTWKQICDKHWTASNSRVVCGMFGFPGEKTYNAKVYKMFAARKKQQYWPFSMDCTGTEAHISSCKLGTQVSLDPVKNVTCENGLPAVVSCVPGQIFSPDGPSRFRKAYKPEQPLVRLRGGANIGEGRVEVLKNGEWGTICDDKWDLVSASVVCRELGFGSAKEAIIGSRLGQGIGPIHLNEIECNGTEKSIIDCKFNVESQGCNHEEDAGVRCNVPAMGFHKKLRLNGGRNPYEGRVEVLVERNGSLVWGKVCGENWGIVEAMVVCRQLGLGFASNAFQETWYWHGNIDANKVVLSGVKCSGTELSLAHCHHDGEDVACPQGGVQYGAGVACSETAPDLVLNAEIVQQSTYLEDRPMFMLQCAMEENCLSASAAQTNPTTGYRRLLRFSSQIHNNGQSDFRPKNGRHAWIWHDCHRHYHSMEVFTHYDLLNLNGTKVAEGHKASFCLEDTECEGDIQKSYECANFGEQGITMGCWDVYRHDIDCQWVDITDVPPGDYLFQVVINPYYEVAESDFTNNIMKCRARYDGHRIWMYNCHIGGSFSEETEKKFEHFSGLINNQLSSRPVPAPSRPLQRVQTQEEWVFQRLEPGKAFEGPLKGKSSQGGTPGALVLTDKFSIVLKKSGTKAT

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JACDTQ010001259
EMBL· GenBank· DDBJ
KAF5923556.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

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