A0A7J7F3D9 · A0A7J7F3D9_DICBM
- ProteinATP-binding cassette sub-family B member 6
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids840 (go to sequence)
- Protein existenceInferred from homology
- Annotation score4/5
Function
Catalytic activity
- ATP + H2O + heme b(in) = ADP + H+ + heme b(out) + phosphateThis reaction proceeds in the forward direction.
CHEBI:30616 + CHEBI:15377 + heme b (in)CHEBI:60344= CHEBI:456216 + CHEBI:15378 + heme b (out)CHEBI:60344+ CHEBI:43474 - ATP + H2O + pheophorbide a(in) = ADP + H+ + pheophorbide a(out) + phosphateThis reaction proceeds in the forward direction.
- ATP + H2O + protoporphyrin IX(in) = ADP + H+ + phosphate + protoporphyrin IX(out)This reaction proceeds in the forward direction.
- ATP + H2O + uroporphyrin I(in) = ADP + H+ + phosphate + uroporphyrin I(out)This reaction proceeds in the forward direction.
- ATP + H2O + uroporphyrin III(in) = ADP + H+ + phosphate + uroporphyrin III(out)This reaction proceeds in the forward direction.
- ATP + coproporphyrin I(in) + H2O = ADP + coproporphyrin I(out) + H+ + phosphateThis reaction proceeds in the forward direction.
- ATP + coproporphyrin III(in) + H2O = ADP + coproporphyrin III(out) + H+ + phosphateThis reaction proceeds in the forward direction.
- ATP + coproporphyrinogen III(in) + H2O = ADP + coproporphyrinogen III(out) + H+ + phosphateThis reaction proceeds in the forward direction.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | early endosome membrane | |
Cellular Component | extracellular region | |
Cellular Component | Golgi membrane | |
Cellular Component | lysosomal membrane | |
Cellular Component | melanosome membrane | |
Cellular Component | mitochondrial outer membrane | |
Cellular Component | multivesicular body membrane | |
Molecular Function | ABC-type transporter activity | |
Molecular Function | ATP binding | |
Molecular Function | ATP hydrolysis activity |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameATP-binding cassette sub-family B member 6
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Laurasiatheria > Perissodactyla > Rhinocerotidae > Diceros
Accessions
- Primary accessionA0A7J7F3D9
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Golgi apparatus membrane ; Multi-pass membrane protein
Membrane ; Multi-pass membrane protein
Mitochondrion outer membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 27-49 | Helical | ||||
Sequence: FFFTLVPSTLMGLGALALVLALP | ||||||
Transmembrane | 70-93 | Helical | ||||
Sequence: VAPYGLQLLLATLQVALPLAGLVG | ||||||
Transmembrane | 105-127 | Helical | ||||
Sequence: GYLLLASILGTLASACGLGLLVV | ||||||
Transmembrane | 148-168 | Helical | ||||
Sequence: VGLLLFWTVAFAAENLALVSW | ||||||
Transmembrane | 188-207 | Helical | ||||
Sequence: LWVLRYVVSGGLFVLGLWAP | ||||||
Transmembrane | 385-407 | Helical | ||||
Sequence: LLSYLVFSIIPTLADIIIGIIYF | ||||||
Transmembrane | 413-434 | Helical | ||||
Sequence: AWFGLIVFLCMSLYLALTIVVT | ||||||
Transmembrane | 505-523 | Helical | ||||
Sequence: LVIGLGLLAGSLLCAYFVG | ||||||
Transmembrane | 529-549 | Helical | ||||
Sequence: VGDFVLFGTYILQLYGPLNWF |
Keywords
- Cellular component
PTM/Processing
Keywords
- PTM
Interaction
Subunit
Homodimer.
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 268-558 | ABC transmembrane type-1 | ||||
Sequence: FICVGLMALDRGLNVLVPIFYRDIVNLLTEKAPWSSVAWTVTTYVFLKFLQGGGTGSTGFVSNLRTFLWIRVQQFTSRQLELRLFSHLHELSLRWHLGRRTGEVLRIVDRGTSSVTGLLSYLVFSIIPTLADIIIGIIYFSMFFNAWFGLIVFLCMSLYLALTIVVTEWRAKFRRAMNIQENATRARAVDSLLNFETVKYYNAEGYEVERYREAIIKFQDLEWKSNASLVLLNQTQNLVIGLGLLAGSLLCAYFVGKQKLQVGDFVLFGTYILQLYGPLNWFGTYYRMIQA | ||||||
Domain | 592-826 | ABC transporter | ||||
Sequence: IEFENVHFSYASGRETLQDVSFTVMPGQTLALVGPSGAGKSTILRLLFRFYDVSSGCIRIDGQDVSQVTQISLRSHIGVVPQDTVLFNDTIANNIRYGRITAGNDEVEAAAQAAGIHDAILAFPEGYKTQVGERGLKLSGGEKQRVAIARTILKAPDIILLDEATSALDTPNERAIQASLAKVCANRTTIVVAHRLSTVVNADQILVLKDGCIVERGRHDALLSQGGVYADVWEL |
Sequence similarities
Belongs to the ABC transporter superfamily. ABCB family. Heavy Metal importer (TC 3.A.1.210) subfamily.
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length840
- Mass (Da)92,850
- Last updated2021-04-07 v1
- Checksum5C197244FDAB47E7
Keywords
- Technical term