A0A7J7EFE6 · A0A7J7EFE6_DICBM
- ProteinInositol-3-phosphate synthase 1
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids513 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
Key enzyme in myo-inositol biosynthesis pathway that catalyzes the conversion of glucose 6-phosphate to 1-myo-inositol 1-phosphate in a NAD-dependent manner. Rate-limiting enzyme in the synthesis of all inositol-containing compounds.
Catalytic activity
- D-glucose 6-phosphate = 1D-myo-inositol 3-phosphate
Cofactor
Pathway
Polyol metabolism; myo-inositol biosynthesis; myo-inositol from D-glucose 6-phosphate: step 1/2.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | inositol-3-phosphate synthase activity | |
Biological Process | inositol biosynthetic process | |
Biological Process | phospholipid biosynthetic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameInositol-3-phosphate synthase 1
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Laurasiatheria > Perissodactyla > Rhinocerotidae > Diceros
Accessions
- Primary accessionA0A7J7EFE6
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Structure
Sequence
- Sequence statusComplete
- Length513
- Mass (Da)56,084
- Last updated2021-04-07 v1
- Checksum558D75DFA3A5187D
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
JACDTQ010003249 EMBL· GenBank· DDBJ | KAF5914401.1 EMBL· GenBank· DDBJ | Genomic DNA |