A0A7J7E861 · A0A7J7E861_DICBM
- ProteinAldehyde dehydrogenase
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids519 (go to sequence)
- Protein existenceInferred from homology
- Annotation score4/5
Function
Catalytic activity
- (2E)-hexadecenal + H2O + NAD+ = (E)-hexadec-2-enoate + 2 H+ + NADH
- 2 H+ + hexadecanoate + NADH = H2O + hexadecanal + NAD+
- 2,6,10,14-tetramethylpentadecanal + H2O + NAD+ = 2,6,10,14-tetramethylpentadecanoate + 2 H+ + NADH
- 22-oxodocosanoate + H2O + NAD+ = docosanedioate + 2 H+ + NADH
- H2O + NAD+ + octadecanal = 2 H+ + NADH + octadecanoate
- H2O + NAD+ + octanal = 2 H+ + NADH + octanoate
- H2O + NAD+ + tetradecanal = 2 H+ + NADH + tetradecanoate
- H2O + heptanal + NAD+ = 2 H+ + heptanoate + NADH
- a fatty aldehyde + H2O + NAD+ = a fatty acid + 2 H+ + NADH
- decanal + H2O + NAD+ = decanoate + 2 H+ + NADH
- dodecanoate + 2 H+ + NADH = dodecanal + H2O + NAD+
Features
Showing features for active site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Active site | 207 | |||||
Sequence: E | ||||||
Active site | 241 | |||||
Sequence: C |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | endoplasmic reticulum membrane | |
Molecular Function | 3-chloroallyl aldehyde dehydrogenase activity | |
Molecular Function | aldehyde dehydrogenase (NAD+) activity | |
Biological Process | cellular aldehyde metabolic process | |
Biological Process | fatty acid metabolic process |
Keywords
- Molecular function
- Biological process
Names & Taxonomy
Protein names
- Recommended nameAldehyde dehydrogenase
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Laurasiatheria > Perissodactyla > Rhinocerotidae > Diceros
Accessions
- Primary accessionA0A7J7E861
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Endoplasmic reticulum membrane ; Single-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 464-480 | Helical | ||||
Sequence: LSLLFLAFLGIVVALLV |
Keywords
- Cellular component
Interaction
Subunit
Homodimer.
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 3-421 | Aldehyde dehydrogenase | ||||
Sequence: REVQRVRDAFLSGRSRPLRFRLQQLEALRRMVQEREKDILAAVAADLCKSELNAYSQEVLSILGEVDLALEKLPEWVTAKPVEKNLLTMLDEAYIQPEPLGVVLIIGAWNYPFVVTIQPLIGAIAAGNAAIIKPSELSENTAKMLAKLLPQYLDQDLYVVINGGVEETTELLKQRFDHILYTGNTAVGKIVMEAAAKHLTPVTLELGGKSPCYIDKDCDLDVACRRITWGKYMNCGQTCIAPDYILCEPSLQNQIVQKIKETVKEFYGENVKESPDYERIINLRHFKRILSLLEGQKIAFGGETDEATRYIAPTILTDVDSETKVMQEEIFGPILPIVPVKNAEEAIKFINEREKPLAFYVFSHNDKLIKRMIDGTSSGGVTANDVIMHFTLTSLPFGGVGSSGMGVYHGKHSFDTFSH |
Sequence similarities
Belongs to the aldehyde dehydrogenase family.
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length519
- Mass (Da)58,203
- Last updated2021-04-07 v1
- ChecksumFA60F9E1B1BED52A
Keywords
- Technical term