A0A7J5QB49 · A0A7J5QB49_9BACE

  • Protein
    Erythronate-4-phosphate dehydrogenase
  • Gene
    pdxB
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Catalyzes the oxidation of erythronate-4-phosphate to 3-hydroxy-2-oxo-4-phosphonooxybutanoate.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Pathway

Cofactor biosynthesis; pyridoxine 5'-phosphate biosynthesis; pyridoxine 5'-phosphate from D-erythrose 4-phosphate: step 2/5.

Features

Showing features for binding site, active site.

TypeIDPosition(s)Description
Binding site46substrate
Binding site67substrate
Binding site147NAD+ (UniProtKB | ChEBI)
Active site209
Binding site233NAD+ (UniProtKB | ChEBI)
Active site238
Active site255Proton donor
Binding site258NAD+ (UniProtKB | ChEBI)
Binding site259substrate

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular Function4-phosphoerythronate dehydrogenase activity
Molecular FunctionNAD binding
Molecular Functionprotein dimerization activity
Biological Processpyridoxine biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Erythronate-4-phosphate dehydrogenase
  • EC number

Gene names

    • Name
      pdxB
    • ORF names
      GAZ43_12335

Organism names

  • Taxonomic identifier
  • Strain
    • BIOML-A16
  • Taxonomic lineage
    Bacteria > Bacteroidota > Bacteroidia > Bacteroidales > Bacteroidaceae > Bacteroides

Accessions

  • Primary accession
    A0A7J5QB49

Proteomes

Subcellular Location

Keywords

Interaction

Subunit

Homodimer.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain14-280D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Domain108-257D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
Domain300-345Erythronate-4-phosphate dehydrogenase dimerisation

Sequence similarities

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    346
  • Mass (Da)
    39,066
  • Last updated
    2021-04-07 v1
  • Checksum
    C254AA15BE425E48
MKIIIDNKIPFIKEAIQRIADEVVYVPGKDFTPELVRDADALIVRTRTHCNRNLLEGSRVKFIATATIGFDHIDTEYCKQAGIEWTNAPGCNSASVAQYIQSSLLVWKSCRNKKLNELTIGIIGVGNVGSKVAKVARDFGMRVLLNDLPREEKEGTELFASLKKIAEECDIITFHVPLYKEGKYKTFHLADENFFQSLKRKPAIINTSRGEVIDTDALLKALDSRIISDAIIDVWEHEPEINRELLEKAFIGTPHIAGYSADGKANATRMSLDAICKFFQIEADYKINAPAPASPIIHAKNHEEAILQIYNPVEDSTRLKNQPEQFETLRGDYPLRREETAYLIKY

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
WDCP01000025
EMBL· GenBank· DDBJ
KAB6339110.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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