A0A7J5Q0R9 · A0A7J5Q0R9_9BACE
- ProteinL-aspartate dehydrogenase
- GenenadX
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids262 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate.
Miscellaneous
The iminoaspartate product is unstable in aqueous solution and can decompose to oxaloacetate and ammonia.
Catalytic activity
- H2O + L-aspartate + NAD+ = H+ + NADH + NH4+ + oxaloacetate
Pathway
Cofactor biosynthesis; NAD+ biosynthesis; iminoaspartate from L-aspartate (dehydrogenase route): step 1/1.
Features
Showing features for binding site.
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | aspartate dehydrogenase activity | |
Molecular Function | NAD binding | |
Molecular Function | NADP binding | |
Molecular Function | oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor | |
Biological Process | NAD biosynthetic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameL-aspartate dehydrogenase
- EC number
Gene names
Organism names
- Organism
- Strains
- Taxonomic lineageBacteria > Bacteroidota > Bacteroidia > Bacteroidales > Bacteroidaceae > Bacteroides
Accessions
- Primary accessionA0A7J5Q0R9
Proteomes
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 8-125 | Aspartate/homoserine dehydrogenase NAD-binding | ||||
Sequence: GCGRLAGIVADAVVKGLLPDYDLVGVYSRTASKAAHIVHKMQQHGKPCIACATLEELLALKPDYLVESASPAAMRELALPALRNGTSVITLSIGALADETFYQEVAETAKANGTRIYI | ||||||
Domain | 170-242 | Aspartate dehydrogenase | ||||
Sequence: TEQRTVFSGSAAEAIRLFPTKVNVTVAASRASVGPENMQVSIQSTPGFVGDTQRVEIKNDQVHAVVDIYSATS |
Sequence similarities
Belongs to the L-aspartate dehydrogenase family.
Family and domain databases
Sequence
- Sequence statusComplete
- Length262
- Mass (Da)27,616
- Last updated2021-04-07 v1
- Checksum8F165934EF95543A