A0A7I8DGC2 · A0A7I8DGC2_9FIRM
- ProteinRelease factor glutamine methyltransferase
- GeneprmC
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids284 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.
Catalytic activity
- L-glutaminyl-[peptide chain release factor] + S-adenosyl-L-methionine = H+ + N5-methyl-L-glutaminyl-[peptide chain release factor] + S-adenosyl-L-homocysteine
Features
Showing features for binding site.
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | nucleic acid binding | |
Molecular Function | protein-(glutamine-N5) methyltransferase activity | |
Molecular Function | protein-glutamine N-methyltransferase activity | |
Biological Process | methylation |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameRelease factor glutamine methyltransferase
- EC number
- Short namesRF MTase
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Bacillota > Clostridia > Lachnospirales > Lachnospiraceae > Anaerocolumna
Accessions
- Primary accessionA0A7I8DGC2
Proteomes
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 6-76 | Release factor glutamine methyltransferase N-terminal | ||||
Sequence: DALQKGKKVLKDNNIDNGEYDAWLLLAFCFELNRAAYLANPLKEIFQDDLDAYMDLIGKRSKHIPLQYITG | ||||||
Domain | 101-185 | Methyltransferase small | ||||
Sequence: LVMEALKVSKDKEILDICSGSGCILLSLLKLGGARSGLGADISETALLVSRENAKKLGVTAEFIKSDIYSQIDKTYDIIVSNPPY |
Sequence similarities
Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
Family and domain databases
Sequence
- Sequence statusComplete
- Length284
- Mass (Da)31,762
- Last updated2021-04-07 v1
- ChecksumCED3ACE686F58869
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AP023368 EMBL· GenBank· DDBJ | BCJ97432.1 EMBL· GenBank· DDBJ | Genomic DNA |