A0A7I2V4X6 · A0A7I2V4X6_HUMAN
- ProteinHepatocyte growth factor-regulated tyrosine kinase substrate
- GeneHGS
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids167 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score1/5
Function
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Molecular Function | phosphatidylinositol binding | |
Molecular Function | ubiquitin binding |
Names & Taxonomy
Protein names
- Submitted names
Gene names
Organism names
- Organism
- Taxonomic lineagecellular organisms > Eukaryota (eucaryotes) > Opisthokonta > Metazoa (metazoans) > Eumetazoa > Bilateria > Deuterostomia > Chordata (chordates) > Craniata > Vertebrata (vertebrates) > Gnathostomata (jawed vertebrates) > Teleostomi > Euteleostomi (bony vertebrates) > Sarcopterygii > Dipnotetrapodomorpha > Tetrapoda (tetrapods) > Amniota (amniotes) > Mammalia (mammals) > Theria > Eutheria (placentals) > Boreoeutheria > Euarchontoglires > Primates > Haplorrhini > Simiiformes > Catarrhini > Hominoidea (apes) > Hominidae (great apes) > Homininae > Homo
Accessions
- Primary accessionA0A7I2V4X6
Proteomes
Organism-specific databases
Disease & Variants
Variants
We now provide the "Disease & Variants" viewer in its own tab.
The viewer provides 134 variants from UniProt as well as other sources including ClinVar and dbSNP.
Genetic variation databases
PTM/Processing
Features
Showing features for modified residue (large scale data).
Type | ID | Position(s) | Source | Description | |||
---|---|---|---|---|---|---|---|
Modified residue (large scale data) | 132 | PRIDE | Phosphotyrosine | ||||
Sequence: Y |
Proteomic databases
Expression
Gene expression databases
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 15-143 | VHS | ||||
Sequence: ATSQLLLETDWESILQICDLIRQGDTQAKYAVNSIKKKVNDKNPHVALYALEVMESVVKNCGQTVHDEVANKQTMEELKDLLKRQVEVNVRNKILYLIQAWAHAFRNEPKYKVVQDTYQIMKVEGHVFP |
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length167
- Mass (Da)19,144
- Last updated2021-04-07 v1
- Checksum49B6C13DF8A8BD3F
Computationally mapped potential isoform sequences
There are 63 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
O14964 | HGS_HUMAN | HGS | 777 | ||
A0A7I2YQD1 | A0A7I2YQD1_HUMAN | HGS | 458 | ||
A0A7I2YQM4 | A0A7I2YQM4_HUMAN | HGS | 50 | ||
A0A7I2YQM9 | A0A7I2YQM9_HUMAN | HGS | 44 | ||
A0A7I2YQH7 | A0A7I2YQH7_HUMAN | HGS | 70 | ||
A0A7I2YQS8 | A0A7I2YQS8_HUMAN | HGS | 44 | ||
A0A7I2YQP0 | A0A7I2YQP0_HUMAN | HGS | 51 | ||
A0A7I2YQU5 | A0A7I2YQU5_HUMAN | HGS | 145 | ||
A0A7I2YQY0 | A0A7I2YQY0_HUMAN | HGS | 46 | ||
I3L346 | I3L346_HUMAN | HGS | 37 | ||
I3L326 | I3L326_HUMAN | HGS | 41 | ||
I3L2H4 | I3L2H4_HUMAN | HGS | 67 | ||
I3L1P5 | I3L1P5_HUMAN | HGS | 536 | ||
I3L1E3 | I3L1E3_HUMAN | HGS | 292 | ||
I3L1F1 | I3L1F1_HUMAN | HGS | 85 | ||
I3L165 | I3L165_HUMAN | HGS | 71 | ||
A0A7I2V6E0 | A0A7I2V6E0_HUMAN | HGS | 710 | ||
A0A7I2V2D8 | A0A7I2V2D8_HUMAN | HGS | 767 | ||
A0A7I2V307 | A0A7I2V307_HUMAN | HGS | 783 | ||
A0A7I2V319 | A0A7I2V319_HUMAN | HGS | 89 | ||
A0A7I2V2K1 | A0A7I2V2K1_HUMAN | HGS | 50 | ||
A0A7I2V2K2 | A0A7I2V2K2_HUMAN | HGS | 737 | ||
A0A7I2V2R9 | A0A7I2V2R9_HUMAN | HGS | 768 | ||
A0A7I2V310 | A0A7I2V310_HUMAN | HGS | 30 | ||
A0A7I2V331 | A0A7I2V331_HUMAN | HGS | 89 | ||
A0A7I2V2M1 | A0A7I2V2M1_HUMAN | HGS | 16 | ||
A0A7I2V2M4 | A0A7I2V2M4_HUMAN | HGS | 33 | ||
A0A7I2V2W5 | A0A7I2V2W5_HUMAN | HGS | 768 | ||
A0A7I2V363 | A0A7I2V363_HUMAN | HGS | 34 | ||
A0A7I2V3A5 | A0A7I2V3A5_HUMAN | HGS | 66 | ||
A0A7I2V3C3 | A0A7I2V3C3_HUMAN | HGS | 97 | ||
A0A7I2V3I8 | A0A7I2V3I8_HUMAN | HGS | 761 | ||
A0A7I2V3J3 | A0A7I2V3J3_HUMAN | HGS | 777 | ||
A0A7I2V3E9 | A0A7I2V3E9_HUMAN | HGS | 39 | ||
A0A7I2V3F9 | A0A7I2V3F9_HUMAN | HGS | 765 | ||
A0A7I2V3L0 | A0A7I2V3L0_HUMAN | HGS | 40 | ||
A0A7I2V3Q7 | A0A7I2V3Q7_HUMAN | HGS | 63 | ||
A0A7I2V3N6 | A0A7I2V3N6_HUMAN | HGS | 39 | ||
A0A7I2V3Z1 | A0A7I2V3Z1_HUMAN | HGS | 690 | ||
A0A7I2V468 | A0A7I2V468_HUMAN | HGS | 12 | ||
A0A7I2V4M9 | A0A7I2V4M9_HUMAN | HGS | 80 | ||
A0A7I2V4J7 | A0A7I2V4J7_HUMAN | HGS | 143 | ||
A0A7I2V558 | A0A7I2V558_HUMAN | HGS | 46 | ||
A0A7I2V569 | A0A7I2V569_HUMAN | HGS | 57 | ||
A0A7I2V4Z5 | A0A7I2V4Z5_HUMAN | HGS | 56 | ||
A0A7I2V5E7 | A0A7I2V5E7_HUMAN | HGS | 41 | ||
A0A7I2V5A2 | A0A7I2V5A2_HUMAN | HGS | 757 | ||
A0A7I2V5A3 | A0A7I2V5A3_HUMAN | HGS | 800 | ||
A0A7I2V5B7 | A0A7I2V5B7_HUMAN | HGS | 88 | ||
A0A7I2V5C4 | A0A7I2V5C4_HUMAN | HGS | 60 | ||
A0A7I2V5D6 | A0A7I2V5D6_HUMAN | HGS | 145 | ||
A0A7I2V5E5 | A0A7I2V5E5_HUMAN | HGS | 65 | ||
A0A7I2V5N3 | A0A7I2V5N3_HUMAN | HGS | 64 | ||
A0A7I2V605 | A0A7I2V605_HUMAN | HGS | 103 | ||
A0A7I2V611 | A0A7I2V611_HUMAN | HGS | 66 | ||
A0A7I2V616 | A0A7I2V616_HUMAN | HGS | 25 | ||
A0A7I2V5L9 | A0A7I2V5L9_HUMAN | HGS | 75 | ||
A0A7I2V5V1 | A0A7I2V5V1_HUMAN | HGS | 117 | ||
A0A7I2V5W6 | A0A7I2V5W6_HUMAN | HGS | 64 | ||
A0A7I2V674 | A0A7I2V674_HUMAN | HGS | 65 | ||
A0A7I2V5X2 | A0A7I2V5X2_HUMAN | HGS | 74 | ||
A0A7I2V628 | A0A7I2V628_HUMAN | HGS | 54 | ||
A0A7I2V637 | A0A7I2V637_HUMAN | HGS | 795 |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AC139530 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. |