A0A7I2V4X6 · A0A7I2V4X6_HUMAN

  • Protein
    Hepatocyte growth factor-regulated tyrosine kinase substrate
  • Gene
    HGS
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Evidence at protein level
  • Annotation score
    1/5

Function

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Molecular Functionphosphatidylinositol binding
Molecular Functionubiquitin binding

Names & Taxonomy

Protein names

  • Submitted names
    • Hepatocyte growth factor-regulated tyrosine kinase substrate

Gene names

    • Name
      HGS

Organism names

Accessions

  • Primary accession
    A0A7I2V4X6

Proteomes

Organism-specific databases

Disease & Variants

Variants

We now provide the "Disease & Variants" viewer in its own tab.

The viewer provides 134 variants from UniProt as well as other sources including ClinVar and dbSNP.

Go to variant viewer

Genetic variation databases

PTM/Processing

Features

Showing features for modified residue (large scale data).

TypeIDPosition(s)SourceDescription
Modified residue (large scale data)132PRIDEPhosphotyrosine

Proteomic databases

Expression

Gene expression databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain15-143VHS

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    167
  • Mass (Da)
    19,144
  • Last updated
    2021-04-07 v1
  • Checksum
    49B6C13DF8A8BD3F
MGRGSGTFERLLDKATSQLLLETDWESILQICDLIRQGDTQAKYAVNSIKKKVNDKNPHVALYALEVMESVVKNCGQTVHDEVANKQTMEELKDLLKRQVEVNVRNKILYLIQAWAHAFRNEPKYKVVQDTYQIMKVEGHVFPEFKESDAMFAAERRPPPAACTLHL

Computationally mapped potential isoform sequences

There are 63 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
O14964HGS_HUMANHGS777
A0A7I2YQD1A0A7I2YQD1_HUMANHGS458
A0A7I2YQM4A0A7I2YQM4_HUMANHGS50
A0A7I2YQM9A0A7I2YQM9_HUMANHGS44
A0A7I2YQH7A0A7I2YQH7_HUMANHGS70
A0A7I2YQS8A0A7I2YQS8_HUMANHGS44
A0A7I2YQP0A0A7I2YQP0_HUMANHGS51
A0A7I2YQU5A0A7I2YQU5_HUMANHGS145
A0A7I2YQY0A0A7I2YQY0_HUMANHGS46
I3L346I3L346_HUMANHGS37
I3L326I3L326_HUMANHGS41
I3L2H4I3L2H4_HUMANHGS67
I3L1P5I3L1P5_HUMANHGS536
I3L1E3I3L1E3_HUMANHGS292
I3L1F1I3L1F1_HUMANHGS85
I3L165I3L165_HUMANHGS71
A0A7I2V6E0A0A7I2V6E0_HUMANHGS710
A0A7I2V2D8A0A7I2V2D8_HUMANHGS767
A0A7I2V307A0A7I2V307_HUMANHGS783
A0A7I2V319A0A7I2V319_HUMANHGS89
A0A7I2V2K1A0A7I2V2K1_HUMANHGS50
A0A7I2V2K2A0A7I2V2K2_HUMANHGS737
A0A7I2V2R9A0A7I2V2R9_HUMANHGS768
A0A7I2V310A0A7I2V310_HUMANHGS30
A0A7I2V331A0A7I2V331_HUMANHGS89
A0A7I2V2M1A0A7I2V2M1_HUMANHGS16
A0A7I2V2M4A0A7I2V2M4_HUMANHGS33
A0A7I2V2W5A0A7I2V2W5_HUMANHGS768
A0A7I2V363A0A7I2V363_HUMANHGS34
A0A7I2V3A5A0A7I2V3A5_HUMANHGS66
A0A7I2V3C3A0A7I2V3C3_HUMANHGS97
A0A7I2V3I8A0A7I2V3I8_HUMANHGS761
A0A7I2V3J3A0A7I2V3J3_HUMANHGS777
A0A7I2V3E9A0A7I2V3E9_HUMANHGS39
A0A7I2V3F9A0A7I2V3F9_HUMANHGS765
A0A7I2V3L0A0A7I2V3L0_HUMANHGS40
A0A7I2V3Q7A0A7I2V3Q7_HUMANHGS63
A0A7I2V3N6A0A7I2V3N6_HUMANHGS39
A0A7I2V3Z1A0A7I2V3Z1_HUMANHGS690
A0A7I2V468A0A7I2V468_HUMANHGS12
A0A7I2V4M9A0A7I2V4M9_HUMANHGS80
A0A7I2V4J7A0A7I2V4J7_HUMANHGS143
A0A7I2V558A0A7I2V558_HUMANHGS46
A0A7I2V569A0A7I2V569_HUMANHGS57
A0A7I2V4Z5A0A7I2V4Z5_HUMANHGS56
A0A7I2V5E7A0A7I2V5E7_HUMANHGS41
A0A7I2V5A2A0A7I2V5A2_HUMANHGS757
A0A7I2V5A3A0A7I2V5A3_HUMANHGS800
A0A7I2V5B7A0A7I2V5B7_HUMANHGS88
A0A7I2V5C4A0A7I2V5C4_HUMANHGS60
A0A7I2V5D6A0A7I2V5D6_HUMANHGS145
A0A7I2V5E5A0A7I2V5E5_HUMANHGS65
A0A7I2V5N3A0A7I2V5N3_HUMANHGS64
A0A7I2V605A0A7I2V605_HUMANHGS103
A0A7I2V611A0A7I2V611_HUMANHGS66
A0A7I2V616A0A7I2V616_HUMANHGS25
A0A7I2V5L9A0A7I2V5L9_HUMANHGS75
A0A7I2V5V1A0A7I2V5V1_HUMANHGS117
A0A7I2V5W6A0A7I2V5W6_HUMANHGS64
A0A7I2V674A0A7I2V674_HUMANHGS65
A0A7I2V5X2A0A7I2V5X2_HUMANHGS74
A0A7I2V628A0A7I2V628_HUMANHGS54
A0A7I2V637A0A7I2V637_HUMANHGS795

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AC139530
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.

Genome annotation databases

Similar Proteins

Disclaimer

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