A0A7I2V4F2 · A0A7I2V4F2_HUMAN
- ProteinPeptidylprolyl isomerase G
- GenePPIG
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids679 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score2/5
Function
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Cellular Component | nuclear speck | |
Molecular Function | cyclosporin A binding | |
Molecular Function | peptidyl-prolyl cis-trans isomerase activity | |
Biological Process | protein peptidyl-prolyl isomerization |
Names & Taxonomy
Protein names
- Submitted names
Gene names
Organism names
- Organism
- Taxonomic lineagecellular organisms > Eukaryota (eucaryotes) > Opisthokonta > Metazoa (metazoans) > Eumetazoa > Bilateria > Deuterostomia > Chordata (chordates) > Craniata > Vertebrata (vertebrates) > Gnathostomata (jawed vertebrates) > Teleostomi > Euteleostomi (bony vertebrates) > Sarcopterygii > Dipnotetrapodomorpha > Tetrapoda (tetrapods) > Amniota (amniotes) > Mammalia (mammals) > Theria > Eutheria (placentals) > Boreoeutheria > Euarchontoglires > Primates > Haplorrhini > Simiiformes > Catarrhini > Hominoidea (apes) > Hominidae (great apes) > Homininae > Homo
Accessions
- Primary accessionA0A7I2V4F2
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
Disease & Variants
Variants
We now provide the "Disease & Variants" viewer in its own tab.
The viewer provides 563 variants from UniProt as well as other sources including ClinVar and dbSNP.
Genetic variation databases
PTM/Processing
Features
Showing features for modified residue (large scale data).
Type | ID | Position(s) | Source | Description | ||
---|---|---|---|---|---|---|
Modified residue (large scale data) | 101 | PRIDE | Phosphoserine | |||
Modified residue (large scale data) | 215 | PRIDE | Phosphoserine | |||
Modified residue (large scale data) | 244 | PRIDE | Phosphoserine | |||
Modified residue (large scale data) | 281 | PRIDE | Phosphoserine | |||
Modified residue (large scale data) | 283 | PRIDE | Phosphothreonine | |||
Modified residue (large scale data) | 300 | PRIDE | Phosphoserine | |||
Modified residue (large scale data) | 301 | PRIDE | Phosphoserine | |||
Modified residue (large scale data) | 311 | PRIDE | Phosphoserine | |||
Modified residue (large scale data) | 322 | PRIDE | Phosphoserine | |||
Modified residue (large scale data) | 338 | PRIDE | Phosphoserine | |||
Modified residue (large scale data) | 340 | PRIDE | Phosphoserine | |||
Modified residue (large scale data) | 431 | PRIDE | Phosphoserine | |||
Modified residue (large scale data) | 458 | PRIDE | Phosphoserine | |||
Modified residue (large scale data) | 469 | PRIDE | Phosphoserine | |||
Modified residue (large scale data) | 471 | PRIDE | Phosphoserine | |||
Modified residue (large scale data) | 602 | PRIDE | Phosphoserine | |||
Modified residue (large scale data) | 612 | PRIDE | Phosphoserine | |||
Modified residue (large scale data) | 615 | PRIDE | Phosphoserine | |||
Modified residue (large scale data) | 620 | PRIDE | Phosphoserine | |||
Modified residue (large scale data) | 621 | PRIDE | Phosphoserine | |||
Modified residue (large scale data) | 641 | PRIDE | Phosphoserine | |||
Modified residue (large scale data) | 642 | PRIDE | Phosphoserine | |||
Modified residue (large scale data) | 669 | PRIDE | Phosphoserine | |||
Modified residue (large scale data) | 670 | PRIDE | Phosphoserine | |||
Modified residue (large scale data) | 673 | PRIDE | Phosphothreonine | |||
Modified residue (large scale data) | 678 | PRIDE | Phosphoserine | |||
Proteomic databases
Expression
Gene expression databases
Structure
Family & Domains
Features
Showing features for domain, region, compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 1-104 | PPIase cyclophilin-type | |||
Region | 105-679 | Disordered | |||
Compositional bias | 123-146 | Polar residues | |||
Compositional bias | 156-178 | Basic residues | |||
Compositional bias | 213-236 | Basic and acidic residues | |||
Compositional bias | 252-274 | Basic residues | |||
Compositional bias | 275-293 | Basic and acidic residues | |||
Compositional bias | 300-375 | Basic and acidic residues | |||
Compositional bias | 390-491 | Basic and acidic residues | |||
Compositional bias | 492-506 | Basic residues | |||
Compositional bias | 507-527 | Basic and acidic residues | |||
Compositional bias | 550-613 | Basic and acidic residues | |||
Compositional bias | 628-679 | Basic and acidic residues | |||
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length679
- Mass (Da)80,148
- Last updated2021-04-07 v1
- Checksum65DC052946200D65
Computationally mapped potential isoform sequences
There are 9 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
Q13427 | PPIG_HUMAN | PPIG | 754 | ||
C9J679 | C9J679_HUMAN | PPIG | 104 | ||
C9JM79 | C9JM79_HUMAN | PPIG | 487 | ||
C9JN15 | C9JN15_HUMAN | PPIG | 246 | ||
E9PG73 | E9PG73_HUMAN | PPIG | 739 | ||
A0A7I2V2U3 | A0A7I2V2U3_HUMAN | PPIG | 65 | ||
A0A7I2V4W3 | A0A7I2V4W3_HUMAN | PPIG | 133 | ||
A0A7I2V5Q5 | A0A7I2V5Q5_HUMAN | PPIG | 751 | ||
A0A7I2V629 | A0A7I2V629_HUMAN | PPIG | 732 |
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 123-146 | Polar residues | |||
Compositional bias | 156-178 | Basic residues | |||
Compositional bias | 213-236 | Basic and acidic residues | |||
Compositional bias | 252-274 | Basic residues | |||
Compositional bias | 275-293 | Basic and acidic residues | |||
Compositional bias | 300-375 | Basic and acidic residues | |||
Compositional bias | 390-491 | Basic and acidic residues | |||
Compositional bias | 492-506 | Basic residues | |||
Compositional bias | 507-527 | Basic and acidic residues | |||
Compositional bias | 550-613 | Basic and acidic residues | |||
Compositional bias | 628-679 | Basic and acidic residues | |||
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AC016772 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. | |
AC093899 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. |