A0A7H1D395 · A0A7H1D395_WNV
- ProteinGenome polyprotein
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids3434 (go to sequence)
- Protein existencePredicted
- Annotation score5/5
Function
Catalytic activity
- ATP + H2O = ADP + phosphate + H+
Features
Showing features for active site, binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Active site | 1556 | Charge relay system; for serine protease NS3 activity | |||
Active site | 1580 | Charge relay system; for serine protease NS3 activity | |||
Active site | 1640 | Charge relay system; for serine protease NS3 activity | |||
Binding site | 2585 | S-adenosyl-L-methionine (UniProtKB | ChEBI) | |||
Binding site | 2615 | S-adenosyl-L-methionine (UniProtKB | ChEBI) | |||
Binding site | 2616 | S-adenosyl-L-methionine (UniProtKB | ChEBI) | |||
Binding site | 2633 | S-adenosyl-L-methionine (UniProtKB | ChEBI) | |||
Binding site | 2634 | S-adenosyl-L-methionine (UniProtKB | ChEBI) | |||
Binding site | 2660 | S-adenosyl-L-methionine (UniProtKB | ChEBI) | |||
Binding site | 2661 | S-adenosyl-L-methionine (UniProtKB | ChEBI) | |||
Binding site | 2749 | S-adenosyl-L-methionine (UniProtKB | ChEBI) | |||
Binding site | 2969 | Zn2+ 1 (UniProtKB | ChEBI) | |||
Binding site | 2973 | Zn2+ 1 (UniProtKB | ChEBI) | |||
Binding site | 2978 | Zn2+ 1 (UniProtKB | ChEBI) | |||
Binding site | 2981 | Zn2+ 1 (UniProtKB | ChEBI) | |||
Binding site | 3246 | Zn2+ 2 (UniProtKB | ChEBI) | |||
Binding site | 3262 | Zn2+ 2 (UniProtKB | ChEBI) | |||
Binding site | 3381 | Zn2+ 2 (UniProtKB | ChEBI) | |||
GO annotations
Keywords
- Molecular function
- Biological process
- Ligand
Names & Taxonomy
Protein names
- Recommended nameGenome polyprotein
Organism names
- Organism
- Strain
- Taxonomic lineageViruses > Riboviria > Orthornavirae > Kitrinoviricota > Flasuviricetes > Amarillovirales > Flaviviridae > Orthoflavivirus > Orthoflavivirus nilense
- Virus hosts
Accessions
- Primary accessionA0A7H1D395
Subcellular Location
UniProt Annotation
GO Annotation
Host endoplasmic reticulum membrane ; Multi-pass membrane protein
Host endoplasmic reticulum membrane ; Peripheral membrane protein
Host endoplasmic reticulum membrane ; Peripheral membrane protein
Virion membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Transmembrane | 44-66 | Helical | |||
Transmembrane | 107-126 | Helical | |||
Transmembrane | 250-269 | Helical | |||
Transmembrane | 276-292 | Helical | |||
Transmembrane | 743-764 | Helical | |||
Transmembrane | 1179-1197 | Helical | |||
Transmembrane | 1217-1235 | Helical | |||
Transmembrane | 1247-1264 | Helical | |||
Transmembrane | 1284-1305 | Helical | |||
Transmembrane | 1342-1366 | Helical | |||
Transmembrane | 1402-1420 | Helical | |||
Transmembrane | 1477-1498 | Helical | |||
Transmembrane | 2174-2195 | Helical | |||
Transmembrane | 2204-2222 | Helical | |||
Transmembrane | 2228-2245 | Helical | |||
Transmembrane | 2257-2279 | Helical | |||
Keywords
- Cellular component
PTM/Processing
Features
Showing features for disulfide bond.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Disulfide bond | 293↔320 | ||||
Disulfide bond | 350↔406 | ||||
Disulfide bond | 364↔395 | ||||
Disulfide bond | 382↔411 | ||||
Disulfide bond | 480↔578 | ||||
Disulfide bond | 595↔626 | ||||
Keywords
- PTM
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 1375-1506 | Flavivirus NS2B | |||
Domain | 1506-1683 | Peptidase S7 | |||
Domain | 1686-1842 | Helicase ATP-binding | |||
Domain | 1853-2018 | Helicase C-terminal | |||
Domain | 2530-2795 | MRNA cap 0-1 NS5-type MT | |||
Domain | 3059-3211 | RdRp catalytic | |||
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length3,434
- Mass (Da)380,296
- Last updated2021-02-10 v1
- MD5 ChecksumBAC4CE49FA9E57E4958BF2290C2439C5
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
MN812761 EMBL· GenBank· DDBJ | QNS31099.1 EMBL· GenBank· DDBJ | Genomic RNA |