A0A7G9XHZ7 · A0A7G9XHZ7_9ROSI
- ProteinAcetyl-coenzyme A carboxylase carboxyl transferase subunit beta, chloroplastic
- GeneaccD
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids634 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO2 group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
Catalytic activity
- N6-carboxybiotinyl-L-lysyl-[protein] + acetyl-CoA = N6-biotinyl-L-lysyl-[protein] + malonyl-CoA
Cofactor
Note: Binds 1 zinc ion per subunit.
Pathway
Lipid metabolism; malonyl-CoA biosynthesis; malonyl-CoA from acetyl-CoA: step 1/1.
Features
Showing features for binding site.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | acetyl-CoA carboxylase complex | |
Cellular Component | chloroplast stroma | |
Molecular Function | acetyl-CoA carboxylase activity | |
Molecular Function | ATP binding | |
Molecular Function | carboxyl- or carbamoyltransferase activity | |
Molecular Function | zinc ion binding | |
Biological Process | fatty acid biosynthetic process | |
Biological Process | malonyl-CoA biosynthetic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameAcetyl-coenzyme A carboxylase carboxyl transferase subunit beta, chloroplastic
- EC number
- Short namesACCase subunit beta ; Acetyl-CoA carboxylase carboxyltransferase subunit beta
Gene names
Encoded on
- Chloroplast
Organism names
- Organism
- Taxonomic lineageEukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Malvales > Thymelaeaceae > Aquilaria
Accessions
- Primary accessionA0A7G9XHZ7
Subcellular Location
Interaction
Subunit
Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein, biotin carboxylase and 2 subunits each of ACCase subunit alpha and ACCase plastid-coded subunit beta (accD).
Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein, biotin carboxylase and two subunits each of ACCase subunit alpha and ACCase plastid-coded subunit beta (accD).
Structure
Family & Domains
Features
Showing features for domain, zinc finger, compositional bias, region.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 258-634 | CoA carboxyltransferase N-terminal | ||||
Sequence: LWVQCEDCYGLNYKKLMKLKMNICEQCGFHLKMNSSDRIELLVDPGTWNPMDEDMVSLDPIEFDSFYSDDEFDLEKELDFDNFPFGKELNPEKELDPEKELDFPFEKELNPEKELDPEKELDPEKELDSDDEDDLDDEDDWDDRYNWYDKLDSEEESYKESSKEEESSNSKEEEPSLEEESSKQSYKDRIDSYQIKTGLTEAVQTGTGQLNGIPIAMGVMDFQFMGGSMGSVVGEKITRLIEYARNQFLPLILVCASGGARMQEGSLSLMQMAKISSTLYDFQSNQKLFYVSILTSPTTGGVTASFGMLGDVIIAEPDAYIAFAGKRVIEQTLNKTVPEGSQEAEYLFDKGLFDQIVPRKLLKGVLSELLQFHHFFV | ||||||
Zinc finger | 262-284 | C4-type | ||||
Sequence: CEDCYGLNYKKLMKLKMNICEQC | ||||||
Compositional bias | 360-379 | Basic and acidic residues | ||||
Sequence: FPFEKELNPEKELDPEKELD | ||||||
Region | 360-445 | Disordered | ||||
Sequence: FPFEKELNPEKELDPEKELDPEKELDSDDEDDLDDEDDWDDRYNWYDKLDSEEESYKESSKEEESSNSKEEEPSLEEESSKQSYKD | ||||||
Compositional bias | 380-400 | Acidic residues | ||||
Sequence: PEKELDSDDEDDLDDEDDWDD | ||||||
Compositional bias | 401-445 | Basic and acidic residues | ||||
Sequence: RYNWYDKLDSEEESYKESSKEEESSNSKEEEPSLEEESSKQSYKD |
Sequence similarities
Belongs to the AccD/PCCB family.
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length634
- Mass (Da)72,845
- Last updated2021-02-10 v1
- ChecksumD3B6CDA0D6520781
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 360-379 | Basic and acidic residues | ||||
Sequence: FPFEKELNPEKELDPEKELD | ||||||
Compositional bias | 380-400 | Acidic residues | ||||
Sequence: PEKELDSDDEDDLDDEDDWDD | ||||||
Compositional bias | 401-445 | Basic and acidic residues | ||||
Sequence: RYNWYDKLDSEEESYKESSKEEESSNSKEEEPSLEEESSKQSYKD |