A0A7G7G713 · A0A7G7G713_9BACT
- ProteinNucleoside diphosphate kinase
- Genendk
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids139 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
Catalytic activity
- a 2'-deoxyribonucleoside 5'-diphosphate + ATP = a 2'-deoxyribonucleoside 5'-triphosphate + ADP
Cofactor
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Binding site | 11 | ATP (UniProtKB | ChEBI) | ||||
Sequence: K | ||||||
Binding site | 59 | ATP (UniProtKB | ChEBI) | ||||
Sequence: F | ||||||
Binding site | 87 | ATP (UniProtKB | ChEBI) | ||||
Sequence: R | ||||||
Binding site | 93 | ATP (UniProtKB | ChEBI) | ||||
Sequence: T | ||||||
Binding site | 104 | ATP (UniProtKB | ChEBI) | ||||
Sequence: R | ||||||
Binding site | 114 | ATP (UniProtKB | ChEBI) | ||||
Sequence: N | ||||||
Active site | 117 | Pros-phosphohistidine intermediate | ||||
Sequence: H |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | ATP binding | |
Molecular Function | metal ion binding | |
Molecular Function | nucleoside diphosphate kinase activity | |
Biological Process | CTP biosynthetic process | |
Biological Process | GTP biosynthetic process | |
Biological Process | UTP biosynthetic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameNucleoside diphosphate kinase
- EC number
- Short namesNDK ; NDP kinase
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Bacteroidota > Cytophagia > Cytophagales > Hymenobacteraceae > Adhaeribacter
Accessions
- Primary accessionA0A7G7G713
Proteomes
Subcellular Location
PTM/Processing
Keywords
- PTM
Interaction
Subunit
Homotetramer.
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 3-137 | Nucleoside diphosphate kinase-like | ||||
Sequence: TNQTFTMIKPDAVQDNHIGAITQMMEADGFRIVSLKKTRLTPERAGEFYAVHKERPFYNDLVKYMSSGPIVAMILEKENAVADFRKLIGATNPANAEEGTIRKKFAKSMEANAVHGSDSDENAQIEGDFFFGAGE |
Sequence similarities
Belongs to the NDK family.
Family and domain databases
Sequence
- Sequence statusComplete
- Length139
- Mass (Da)15,453
- Last updated2021-02-10 v1
- Checksum329D96B3483CC037
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CP055156 EMBL· GenBank· DDBJ | QNF32947.1 EMBL· GenBank· DDBJ | Genomic DNA |