A0A7G7FN66 · A0A7G7FN66_9BACI
- ProteinMultifunctional fusion protein
- GenesecDF
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids747 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | plasma membrane | |
Molecular Function | protein-transporting ATPase activity | |
Biological Process | intracellular protein transmembrane transport | |
Biological Process | protein targeting | |
Biological Process | protein transport by the Sec complex |
Keywords
- Biological process
Names & Taxonomy
Protein names
- Recommended nameMultifunctional fusion protein
Including 2 domains:
- Recommended nameProtein translocase subunit SecD
- Recommended nameProtein-export membrane protein SecF
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Bacillota > Bacilli > Bacillales > Bacillaceae > Metabacillus
Accessions
- Primary accessionA0A7G7FN66
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Cell membrane ; Multi-pass membrane protein
Membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 259-277 | Helical | ||||
Sequence: VLAGIIGISIIFLFMIAFY | ||||||
Transmembrane | 282-299 | Helical | ||||
Sequence: LIAVITLSTYIYVILQVF | ||||||
Transmembrane | 311-332 | Helical | ||||
Sequence: IAALILGVGMAVDANIITYERI | ||||||
Transmembrane | 353-374 | Helical | ||||
Sequence: SFATIFDANITTILAGGVLFFF | ||||||
Transmembrane | 386-409 | Helical | ||||
Sequence: LILSIIVSFITAVFLSRILLALLV | ||||||
Transmembrane | 455-474 | Helical | ||||
Sequence: LFFMLSTVAVIAGIIILLVF | ||||||
Transmembrane | 570-587 | Helical | ||||
Sequence: AMYGVLIAAIGIIIYVAI | ||||||
Transmembrane | 594-615 | Helical | ||||
Sequence: GLASVVALLHDAFFIIAFFSIT | ||||||
Transmembrane | 621-642 | Helical | ||||
Sequence: ITFIAAVLTIVGYSINDTIVTF | ||||||
Transmembrane | 676-694 | Helical | ||||
Sequence: INTVLTVVIAVVALLIFGS | ||||||
Transmembrane | 700-726 | Helical | ||||
Sequence: FSIALLVGLVCGTYSSLFIAAQLWLIW |
Keywords
- Cellular component
Interaction
Subunit
Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 65-120 | Protein translocase subunit SecDF P1 | ||||
Sequence: TVNALQKRANVLGVSEPNIQIEGDDRIRVQLAGVDDQTKAREILSTQAELTFRDYQ | ||||||
Domain | 242-409 | Protein export membrane protein SecD/SecF C-terminal | ||||
Sequence: YSTSVGAQFGEQALDQTVLAGIIGISIIFLFMIAFYRLPGLIAVITLSTYIYVILQVFDWMNGVLTLPGIAALILGVGMAVDANIITYERIKEELKLGRTVRSAFKAGSRRSFATIFDANITTILAGGVLFFFGTSSVKGFATMLILSIIVSFITAVFLSRILLALLV | ||||||
Domain | 551-727 | Protein export membrane protein SecD/SecF C-terminal | ||||
Sequence: TEPNVSTVSPTVGKELAQNAMYGVLIAAIGIIIYVAIRFEFYMGLASVVALLHDAFFIIAFFSITRLEVDITFIAAVLTIVGYSINDTIVTFDRIRELQKKRKVKTVEDLQFIVNRSLQQTFTRSINTVLTVVIAVVALLIFGSSSITNFSIALLVGLVCGTYSSLFIAAQLWLIWK |
Sequence similarities
Belongs to the SecD/SecF family. SecD subfamily.
Belongs to the SecD/SecF family. SecF subfamily.
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length747
- Mass (Da)82,328
- Last updated2021-02-10 v1
- Checksum0D38A68EF0C387E4
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CP055263 EMBL· GenBank· DDBJ | QNF26350.1 EMBL· GenBank· DDBJ | Genomic DNA |