A0A7G7FN66 · A0A7G7FN66_9BACI

Function

function

Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentplasma membrane
Molecular Functionprotein-transporting ATPase activity
Biological Processintracellular protein transmembrane transport
Biological Processprotein targeting
Biological Processprotein transport by the Sec complex

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Multifunctional fusion protein

Including 2 domains:

  • Recommended name
    Protein translocase subunit SecD
  • Recommended name
    Protein-export membrane protein SecF

Gene names

    • Name
      secDF
    • Synonyms
      secD
      , secF
    • ORF names
      HUW50_01540

Organism names

Accessions

  • Primary accession
    A0A7G7FN66

Proteomes

Subcellular Location

Cell membrane
; Multi-pass membrane protein
Membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane259-277Helical
Transmembrane282-299Helical
Transmembrane311-332Helical
Transmembrane353-374Helical
Transmembrane386-409Helical
Transmembrane455-474Helical
Transmembrane570-587Helical
Transmembrane594-615Helical
Transmembrane621-642Helical
Transmembrane676-694Helical
Transmembrane700-726Helical

Keywords

Interaction

Subunit

Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain65-120Protein translocase subunit SecDF P1
Domain242-409Protein export membrane protein SecD/SecF C-terminal
Domain551-727Protein export membrane protein SecD/SecF C-terminal

Sequence similarities

Belongs to the SecD/SecF family. SecD subfamily.
Belongs to the SecD/SecF family. SecF subfamily.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    747
  • Mass (Da)
    82,328
  • Last updated
    2021-02-10 v1
  • Checksum
    0D38A68EF0C387E4
MVKRGRIIAFFLLVLFVGSLIGLNTNRVTNNIILGLDLQGGFEILYEVKPANEGDKITRDVLVSTVNALQKRANVLGVSEPNIQIEGDDRIRVQLAGVDDQTKAREILSTQAELTFRDYQDKEMLNGADLVEGGASQSFDEQGKPNVAIKLKDASKFKEVTQEIVGNAPYNQLVIWLDYAEGDAYQEEATKAEPKFISAPNVDQVFNQTDVTITGDFTIQEAKDLANLLNAGSLPVKLDEMYSTSVGAQFGEQALDQTVLAGIIGISIIFLFMIAFYRLPGLIAVITLSTYIYVILQVFDWMNGVLTLPGIAALILGVGMAVDANIITYERIKEELKLGRTVRSAFKAGSRRSFATIFDANITTILAGGVLFFFGTSSVKGFATMLILSIIVSFITAVFLSRILLALLVESRWLDKKKGYFGVKKKDILSIEETDDDTTAPTKFDQVDFLKYRKLFFMLSTVAVIAGIIILLVFKLNLGIDFASGTRVEVLAGKTITTEEITEEMSKIDLEVDDVVLSGDENEIGVARFTGTLDQQKIAELKNHFKEKYGTEPNVSTVSPTVGKELAQNAMYGVLIAAIGIIIYVAIRFEFYMGLASVVALLHDAFFIIAFFSITRLEVDITFIAAVLTIVGYSINDTIVTFDRIRELQKKRKVKTVEDLQFIVNRSLQQTFTRSINTVLTVVIAVVALLIFGSSSITNFSIALLVGLVCGTYSSLFIAAQLWLIWKGKQLNKKKELPSNVSDEPQV

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP055263
EMBL· GenBank· DDBJ
QNF26350.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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