A0A7G6KLV7 · A0A7G6KLV7_CHRBR

Function

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Catalytic activity

Cofactor

Protein has several cofactor binding sites:
Zn2+ (UniProtKB | Rhea| CHEBI:29105 )

Note: Binds 1 zinc ion per subunit.
chloride (UniProtKB | Rhea| CHEBI:17996 )

Features

Showing features for active site.

TypeIDPosition(s)Description
Active site374Proton acceptor 1
Active site504Proton donor 1

GO annotations

AspectTerm
Cellular Componentapical plasma membrane
Cellular Componentcilium
Cellular Componentcytoplasm
Cellular Componentextracellular space
Molecular Functioncarboxypeptidase activity
Molecular Functionmetal ion binding
Molecular Functionmetallopeptidase activity
Molecular Functionpeptidyl-dipeptidase activity
Biological Processproteolysis

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Angiotensin-converting enzyme
  • EC number

Organism names

  • Taxonomic identifier
  • Strain
    • Flint
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Laurasiatheria > Carnivora > Caniformia > Canidae > Chrysocyon

Accessions

  • Primary accession
    A0A7G6KLV7

Subcellular Location

Apical cell membrane
Cell membrane
; Single-pass type I membrane protein
Cell projection, cilium
Cytoplasm
Secreted

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane738-762Helical

Keywords

PTM/Processing

Features

Showing features for signal, chain, glycosylation, disulfide bond.

TypeIDPosition(s)Description
Signal1-17
ChainPRO_502899144918-802Angiotensin-converting enzyme
Glycosylation52N-linked (GlcNAc...) asparagine
Disulfide bond132↔140
Disulfide bond343↔360
Disulfide bond529↔541
Glycosylation577N-linked (GlcNAc...) asparagine; partial

Keywords

Family & Domains

Features

Showing features for domain, region, compositional bias.

TypeIDPosition(s)Description
Domain613-802Collectrin-like
Region769-802Disordered
Compositional bias782-802Polar residues

Sequence similarities

Belongs to the peptidase M2 family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Fragment
  • Length
    802
  • Mass (Da)
    92,552
  • Last updated
    2021-02-10 v1
  • Checksum
    438569B1CA7690EC
MSGSSWLLLSLAALTAAQSTEDLVKTFLEKFNYEAEELSYQSSLASWNYNINITDENVQKMNNAGAKWSAFYEEQSKLAKTYPLEEIQDSTVKRQLRALQHSGSSVLSADKNQRLNTILNSMSTIYSTGKACNPSNPQECLLLEPGLDDIMENSKDYNERLWAWEGWRSEVGKQLRPLYEEYVALKNEMARANNYEDYGDYWRGDYEEEWENGYNYSRNQLIDDVEHTFTQIMPLYQHLHAYVRTKLMDTYPSYISPTGCLPAHLLGDMWGRFWTNLYPLTVPFGQKPNIDVTNAMVNQSWDARKIFKEAEKFFVSVGLPNMTQEFWENSMLTEPSDSRKVVCHPTAWDLGKGDFRIKMCTKVTMDDFLTAHHEMGHIQYDMAYAAQPFLLRNGANEGFHEAVGEIMSLSAATPNHLKNIGLLPPSFFEDSETEINFLLKQALTIVGTLPFTYMLEKWRWMVFKGEIPKDQWMKTWWEMKRNIVGVVEPVPHDETYCDPASLFHVANDYSFIRYYTRTIYQFQFQEALCQIAKHEGPLHKCDISNSSEAGQKLLEMLKLGKSKPWTYALEIVVGAKNMDVRPLLNYFEPLFTWLKEQNRNSFVGWNTDWSPYADQSIKVRISLKSALGEKAYEWNNNEMYLFRSSIAYAMRQYFSEVKNQTIPFVEDNVWVSDLKPRISFNFFVTSPGNVSDIIPRTEVEEAIRRSRINDVFRLDDNSLEFLGIQPTLGPPYEPPVTIWLIVFGVVMGVVVVGIVLLIFSGIRNRRKNDQARGEENPYASVDLSKGENNPGFQNVDDAQTSF

Features

Showing features for compositional bias, non-terminal residue.

TypeIDPosition(s)Description
Compositional bias782-802Polar residues
Non-terminal residue802

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
MT560523
EMBL· GenBank· DDBJ
QNC68917.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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