A0A7G6KL52 · A0A7G6KL52_AVEFL

Function

function

NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

Catalytic activity

Cofactor

[4Fe-4S] cluster (UniProtKB | Rhea| CHEBI:49883 )

Note: Binds 2 [4Fe-4S] clusters per subunit.

Features

Showing features for binding site.

118020406080100120140160180
TypeIDPosition(s)Description
Binding site64[4Fe-4S] cluster 1 (UniProtKB | ChEBI)
Binding site67[4Fe-4S] cluster 1 (UniProtKB | ChEBI)
Binding site70[4Fe-4S] cluster 1 (UniProtKB | ChEBI)
Binding site74[4Fe-4S] cluster 2 (UniProtKB | ChEBI)
Binding site104[4Fe-4S] cluster 2 (UniProtKB | ChEBI)
Binding site107[4Fe-4S] cluster 2 (UniProtKB | ChEBI)
Binding site110[4Fe-4S] cluster 2 (UniProtKB | ChEBI)
Binding site114[4Fe-4S] cluster 1 (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentchloroplast
Cellular Componentplasma membrane
Cellular Componentthylakoid
Molecular Function4 iron, 4 sulfur cluster binding
Molecular Functioniron ion binding
Molecular FunctionNADH dehydrogenase (ubiquinone) activity
Molecular FunctionNADH:ubiquinone reductase (non-electrogenic) activity
Molecular Functionquinone binding

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    NADH-quinone oxidoreductase subunit I
  • EC number
  • Alternative names
    • NADH dehydrogenase I subunit I
    • NDH-1 subunit I

Gene names

    • Name
      ndhI
    • Synonyms
      nuoI

Encoded on

  • Plastid

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > Liliopsida > Poales > Poaceae > BOP clade > Pooideae > Poodae > Poeae > Poeae Chloroplast Group 2 (Poeae type) > Airinae > Avenella

Accessions

  • Primary accession
    A0A7G6KL52

Subcellular Location

Cell membrane
; Peripheral membrane protein

Keywords

PTM/Processing

Keywords

Interaction

Subunit

NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain55-844Fe-4S ferredoxin-type
Domain95-1244Fe-4S ferredoxin-type

Sequence similarities

Belongs to the complex I 23 kDa subunit family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    180
  • Mass (Da)
    21,187
  • Last updated
    2021-02-10 v1
  • Checksum
    7F2D4DCD0C5C9DEA
MFPMVTGFMSYGQQTIRATRYIGQSFITTLSHTNRLPITIHYPYEKSITPERFRGRIHFEFDKCIACEVCVRVCPIDLPVVDWRFEKDIKRKQLLNYSIDFGVCIFCGNCVEYCPTNCLSMTEEYELSTYDRHELNYNQIALSRLPISIMEDYTIQTIRNSTESKIDEDKSSNSRTITYY

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
MN944893
EMBL· GenBank· DDBJ
QNC67985.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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