A0A7G2FGQ9 · A0A7G2FGQ9_ARATH
- ProteinDNA repair protein REV1
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids1048 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template-dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents.
Cofactor
Note: Binds 2 magnesium ions.
Features
Showing features for binding site.
GO annotations
all annotations | all molecular function | nucleotide binding | molecular_function | nucleic acid binding | dna binding | chromatin binding | dna-binding transcription factor activity | rna binding | cytoskeletal motor activity | catalytic activity | nuclease activity | signaling receptor binding | structural molecule activity | transporter activity | binding | protein binding | translation factor activity, rna binding | lipid binding | kinase activity | transferase activity | hydrolase activity | oxygen binding | enzyme regulator activity | carbohydrate binding | signaling receptor activity | translation regulator activity | transcription regulator activity | other molecular function | all biological process | carbohydrate metabolic process | generation of precursor metabolites and energy | nucleobase-containing compound metabolic process | dna metabolic process | translation | lipid metabolic process | transport | response to stress | cell cycle | cell communication | signal transduction | cell-cell signaling | multicellular organism development | circadian rhythm | biological_process | metabolic process | catabolic process | biosynthetic process | response to light stimulus | response to external stimulus | tropism | response to biotic stimulus | response to abiotic stimulus | response to endogenous stimulus | embryo development | post-embryonic development | fruit ripening | abscission | pollination | flower development | cellular process | programmed cell death | photosynthesis | cellular component organization | cell growth | protein metabolic process | cellular homeostasis | secondary metabolic process | reproductive process | cell differentiation | protein modification process | growth | epigenetic regulation of gene expression | response to chemical | anatomical structure development | regulation of molecular function | other biological process | all cellular component | cellular_component | extracellular region | cell wall | intracellular anatomical structure | nucleus | nuclear envelope | nucleoplasm | nucleolus | cytoplasm | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | cytosol | ribosome | cytoskeleton | plasma membrane | chloroplast | plastid | thylakoid | membrane | external encapsulating structure | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | nucleus | |
Molecular Function | damaged DNA binding | |
Molecular Function | DNA-directed DNA polymerase activity | |
Molecular Function | metal ion binding | |
Biological Process | error-prone translesion synthesis |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameDNA repair protein REV1
- EC number
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis
Accessions
- Primary accessionA0A7G2FGQ9
Proteomes
Subcellular Location
Structure
Family & Domains
Features
Showing features for domain, compositional bias, region.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 26-117 | BRCT | ||||
Sequence: SEKLIFQGVSIFVDGFTIPSHQELKGYMMKYGGRFENYFSRRSVTHIICSNLPDSKVKNLRTFSRGLPVVKPTWIVDSISANRLLGWVPYQL | ||||||
Compositional bias | 141-156 | Polar residues | ||||
Sequence: MASPVTSFQPDTGYSE | ||||||
Region | 141-205 | Disordered | ||||
Sequence: MASPVTSFQPDTGYSEAEEGSSIRADDSEEARDHIDDEIDGVYIENTTPELTEQTGTGDLKSSEM | ||||||
Compositional bias | 160-181 | Basic and acidic residues | ||||
Sequence: GSSIRADDSEEARDHIDDEIDG | ||||||
Compositional bias | 187-202 | Polar residues | ||||
Sequence: TTPELTEQTGTGDLKS | ||||||
Region | 234-262 | Disordered | ||||
Sequence: SDNKSVHANGKNGGKSIATAAGSSTRRHS | ||||||
Domain | 318-499 | UmuC | ||||
Sequence: IIHIDLDCFFVSVVIKNRLELHDKPVAVCHSDNPKGTAEISSANYPARAYGVKAGMFVRHAKDLCPQLVIVPYNFEAYEEVADQFYDILHRHCRKVQALSCDEAFLDVSDLSDVETEVLASTIRNEILETTGCSASAGIGGTMLMARLATRVAKPAGQLYISAEKVEEFLDQLPVGTLPGVG | ||||||
Region | 718-746 | Disordered | ||||
Sequence: RPVTGGVSRLRESNSEESSIQSGDTNSSL | ||||||
Region | 877-902 | Disordered | ||||
Sequence: AFPSHRRQQSSSDVPKETCKKQDEEP | ||||||
Compositional bias | 886-902 | Basic and acidic residues | ||||
Sequence: SSSDVPKETCKKQDEEP |
Sequence similarities
Belongs to the DNA polymerase type-Y family.
Family and domain databases
Sequence
- Sequence statusComplete
- Length1,048
- Mass (Da)116,288
- Last updated2021-02-10 v1
- Checksum5C120CAA661EAE8C
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 141-156 | Polar residues | ||||
Sequence: MASPVTSFQPDTGYSE | ||||||
Compositional bias | 160-181 | Basic and acidic residues | ||||
Sequence: GSSIRADDSEEARDHIDDEIDG | ||||||
Compositional bias | 187-202 | Polar residues | ||||
Sequence: TTPELTEQTGTGDLKS | ||||||
Compositional bias | 886-902 | Basic and acidic residues | ||||
Sequence: SSSDVPKETCKKQDEEP |