A0A7G2F7W5 · A0A7G2F7W5_ARATH
- ProteinS-adenosylmethionine decarboxylase proenzyme
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids363 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
Catalytic activity
- S-adenosyl-L-methionine + H+ = S-adenosyl 3-(methylsulfanyl)propylamine + CO2
Cofactor
Note: Binds 1 pyruvoyl group covalently per subunit.
Pathway
Amine and polyamine biosynthesis; S-adenosylmethioninamine biosynthesis; S-adenosylmethioninamine from S-adenosyl-L-methionine: step 1/1.
Features
Showing features for binding site, site, active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 8 | substrate | |||
Binding site | 68 | substrate | |||
Site | 68-69 | Cleavage (non-hydrolytic); by autolysis | |||
Active site | 69 | Schiff-base intermediate with substrate; via pyruvic acid | |||
Active site | 83 | Proton donor; for catalytic activity | |||
Binding site | 226 | substrate | |||
Active site | 232 | Proton acceptor; for processing activity | |||
Active site | 245 | Proton acceptor; for processing activity | |||
Binding site | 249 | substrate | |||
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | adenosylmethionine decarboxylase activity | |
Biological Process | spermidine biosynthetic process | |
Biological Process | spermine biosynthetic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameS-adenosylmethionine decarboxylase proenzyme
- EC number
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis
Accessions
- Primary accessionA0A7G2F7W5
Proteomes
PTM/Processing
Features
Showing features for chain, modified residue.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Chain | PRO_5042323778 | 1-68 | S-adenosylmethionine decarboxylase beta chain | ||
Modified residue | 69 | Pyruvic acid (Ser); by autocatalysis | |||
Chain | PRO_5042323777 | 69-363 | S-adenosylmethionine decarboxylase alpha chain | ||
Keywords
- PTM
Structure
Sequence
- Sequence statusComplete
- Length363
- Mass (Da)40,174
- Last updated2021-02-10 v1
- Checksum59E0B15E66D38749
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
LR881470 EMBL· GenBank· DDBJ | CAD5331815.1 EMBL· GenBank· DDBJ | Genomic DNA |