A0A7G2F7W5 · A0A7G2F7W5_ARATH

Function

Catalytic activity

Cofactor

pyruvate (UniProtKB | Rhea| CHEBI:15361 )

Note: Binds 1 pyruvoyl group covalently per subunit.

Pathway

Amine and polyamine biosynthesis; S-adenosylmethioninamine biosynthesis; S-adenosylmethioninamine from S-adenosyl-L-methionine: step 1/1.

Features

Showing features for binding site, site, active site.

136350100150200250300350
Type
IDPosition(s)Description
Binding site8substrate
Binding site68substrate
Site68-69Cleavage (non-hydrolytic); by autolysis
Active site69Schiff-base intermediate with substrate; via pyruvic acid
Active site83Proton donor; for catalytic activity
Binding site226substrate
Active site232Proton acceptor; for processing activity
Active site245Proton acceptor; for processing activity
Binding site249substrate

GO annotations

AspectTerm
Molecular Functionadenosylmethionine decarboxylase activity
Biological Processspermidine biosynthetic process
Biological Processspermine biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    S-adenosylmethionine decarboxylase proenzyme
  • EC number

Gene names

    • ORF names
      AT9943_LOCUS19261

Organism names

  • Taxonomic identifier
  • Strain
    • cv. Cdm-0
  • Taxonomic lineage
    Eukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis

Accessions

  • Primary accession
    A0A7G2F7W5

Proteomes

PTM/Processing

Features

Showing features for chain, modified residue.

Type
IDPosition(s)Description
ChainPRO_50423237781-68S-adenosylmethionine decarboxylase beta chain
Modified residue69Pyruvic acid (Ser); by autocatalysis
ChainPRO_504232377769-363S-adenosylmethionine decarboxylase alpha chain

Keywords

Family & Domains

Sequence similarities

Belongs to the eukaryotic AdoMetDC family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    363
  • Mass (Da)
    40,174
  • Last updated
    2021-02-10 v1
  • Checksum
    59E0B15E66D38749
MAMSAIGFEGYEKRLEVTFFEPGLFLDTQGKGLRALAKSQIDEILQPAECTIVSSLSNDQLDSYVLSESSLFIFPYKIVIKTCGTTKLLLSIEPLLRLAGELSLDVKAVRYTRGSFLCPGGQPFPHRNFSEEVSVLDGHFAKLGLSSVAYLMGNDDETKKWHVYSASSANSNNKNNVYTLEMCMTGLDKDKASVFYKNESSSAGSMTDNSGIRKILPQSQICDFEFEPCGYSMNSIEGDAISTIHVTPEDGFSYASFEAVGYDFTTMDLSHLVSKVLTCFEPKQFSVAVHSTVAQKSYDSGLSVDLDDYGCKESTMESLGEERGTVMYQRFEKLGRYYCGSPRSTLKCEWSSNSSCNSEDEKE

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
LR881470
EMBL· GenBank· DDBJ
CAD5331815.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
Help