A0A7D7Y678 · A0A7D7Y678_9MOLU

  • Protein
    Triosephosphate isomerase
  • Gene
    tpiA
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

Catalytic activity

Pathway

Carbohydrate biosynthesis; gluconeogenesis.
Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate from glycerone phosphate: step 1/1.

Features

Showing features for binding site, active site.

125220406080100120140160180200220240
Type
IDPosition(s)Description
Binding site11-13substrate
Active site97Electrophile
Active site169Proton acceptor
Binding site175substrate
Binding site215substrate
Binding site236-237substrate

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular Functiontriose-phosphate isomerase activity
Biological Processgluconeogenesis
Biological Processglyceraldehyde-3-phosphate biosynthetic process
Biological Processglycerol catabolic process
Biological Processglycolytic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Triosephosphate isomerase
  • EC number
  • Short names
    TIM
    ; TPI
  • Alternative names
    • Triose-phosphate isomerase

Gene names

    • Name
      tpiA
    • ORF names
      H3143_02880

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • 56A97T
  • Taxonomic lineage
    Bacteria > Mycoplasmatota > Mollicutes > Mycoplasmataceae > Mycoplasma

Accessions

  • Primary accession
    A0A7D7Y678

Proteomes

Subcellular Location

Keywords

Interaction

Subunit

Homodimer.

Family & Domains

Sequence similarities

Belongs to the triosephosphate isomerase family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    252
  • Mass (Da)
    27,980
  • Last updated
    2020-12-02 v1
  • Checksum
    F4324A18F53B3466
MNSMKRYIFGNWKTYKTTSEVKEFFSVLNQANLTKTNEVVFGVAPVFVHLGLANELKRKECFILAQDANYVMNKANTGTVSYEQLKDIGIDYVIIGHSERRNLFHESDELINQKVKTLLQNKMTPILCIGETLEQYEANQTKAVLKEQLEKDLKGIDSSLLKSLIIAYEPVWAIGTGKTASAQTAQDAIAYIRSVVSSLASEEIANEMPILYGGSVNPENVSELLAQKDINGALVGGASLDPRKFIQLIEAK

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP059674
EMBL· GenBank· DDBJ
QMT98857.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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