A0A7D5YBE6 · A0A7D5YBE6_9ACTN

Function

Features

Showing features for active site.

137615001,0001,5002,0002,5003,0003,500
TypeIDPosition(s)Description
Active site916Proton acceptor; for dehydratase activity
Active site1080Proton donor; for dehydratase activity
Active site2883Proton acceptor; for dehydratase activity
Active site3054Proton donor; for dehydratase activity

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcytoplasm
Cellular Componentplasma membrane
Molecular Function3-oxoacyl-[acyl-carrier-protein] synthase activity
Molecular Functionfatty acid synthase activity
Molecular Functionoxidoreductase activity
Molecular Functionphosphopantetheine binding
Biological ProcessDIM/DIP cell wall layer assembly
Biological Processfatty acid biosynthetic process

Keywords

Names & Taxonomy

Protein names

  • Submitted names
    • SDR family NAD(P)-dependent oxidoreductase

Gene names

    • ORF names
      HZU44_18945

Organism names

  • Taxonomic identifier
  • Strain
    • Africana
  • Taxonomic lineage
    Bacteria > Actinomycetota > Actinomycetes > Micromonosporales > Micromonosporaceae > Micromonospora

Accessions

  • Primary accession
    A0A7D5YBE6

Subcellular Location

PTM/Processing

Keywords

Family & Domains

Features

Showing features for domain, region.

TypeIDPosition(s)Description
Domain37-458Ketosynthase family 3 (KS3)
Region884-1006N-terminal hotdog fold
Domain884-1158PKS/mFAS DH
Region1019-1158C-terminal hotdog fold
Domain1903-1978Carrier
Domain2004-2425Ketosynthase family 3 (KS3)
Region2851-2977N-terminal hotdog fold
Domain2851-3132PKS/mFAS DH
Region2997-3132C-terminal hotdog fold
Domain3612-3687Carrier

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    3,761
  • Mass (Da)
    394,232
  • Last updated
    2020-12-02 v1
  • Checksum
    2965B398C81CF635
MTQGTDEQQKLRTYLRKVTSELLTANRRVRELEERDLEPLAIVGMSCRYPGGASSPQHLWELVEQGRDAITGLPRDRGWDVDTLYDPDPERTGRVYARGGGFLDGVGDFDAAFFGVSPREALAMDPQQRLALEASWEALEDAGIDPTALRGSGTGVFVGALATDYGPAMRAELEGFRLTGTQTSVVSGRIAYTLGLEGPAVSVDTACSSSLVALHLAGQALRLGECSLALVGGVTVLAGPFLLVEFSRQRGLAADGRCKPYAAAADGTGFSDGVGMLVVERLSDARRRGHRVLAVVRGSAVNQDGASNGLTAPNGPAQERVIRQALAVAGLSAAEVDVVEGHGTGTRLGDPIEAQALLATYGRDREVPLWLGSVKSNIGHTSAAAGVAGVIKMVQAMRYGVLPRTLHVDAPSPHVEWDAGRVELLTQARPWVVGGRPRRAGVSSFGISGTNAHVILEEAPRGDVEEAPRGEAEVESVVVPSVVPILVSARSEQALRAQEARLRAFLPGRDLLDVAFSAATTRAHLEYRVALVGEERFAGRPVVGKTAVLFTGQGSQRARMGAGLTYPVFRRVFDEVCGHFDPEVREALVSADGSGLDDTRVTQAALFAVEVALFRLVESFGVRPDFLLGHSVGELAAAHVAGVLSLVDACTLVAARGRLMGALPAGGGMLAVQATEDEISGVAVAAVNGPSAVVVSGSLDELREFQARWSDRKTTWLTVSHAFHSPLMEPMLEEFERVARGLDFRSPRIPIVSNVTGGVVGDEVTDPAYWVRHVREAVRFHDGVRTLREQGVTRFLELGPDAVLTAMARSFLDDDVVLAAALRAKQSEPHAFAAFLAQAHNAGVPVDWAAVLAGGKRIDLPTYAFQHQRYWLMPDTSSLDRVDHPLLTGAVRVGDRDEWVLTGRLSRDLAPWLPDHAVLGTVVVPGTALVELALTAGRHAGTPVVDELTLETPLVVPADAEVRLQVTVGEPGGDGRRAVAVYSHADDSHAGRCHARGVLAAVDDEVLPSPGTPWPPADAEPIGVDALYARLAEMGYEYGPAFQGVEAAWRDGDAVYAEVALAGEYTEAARHFVLHPALFDAALHGGPDLLDRGDGTAPGLPFAFSGVRLDRTGLSRLRVRVTTTAAATLRIDIADDQGGGAGRIDALALRPADSRQLTGAAPGGSLHTLDWIPAPSGTARTDAAADLVIATVDDPSGDDPAERARAVTAWTLDLLQRRLAEPDTATRLVVVTRHAVAVGDEAVDLVMAPVWGLVRSAQSEHPGRFQLVDLPGGEPDPDWVALAATGEPQLAVRGGVPLAPRLTAHKVEPITGAWHLTSEHKGSLEELTLLPSDGERALGVGEVRVGVRAAGLNFRDVLIALGMYPGEAPLGSEAAGVVLEVGAEVTDLVPGDRVLGIVPDAFGPVAVTDRRLVVPMPGSWSFVQGAAVPVVYLTALYGLRDLAGLRQGEKLLVHAAAGGVGMAAVQLAGHVGAEVYATASPAKWDVVRGLGVPAERIASSRDLGFRERFAGGVDVVLNALAGEFVDASLDVLGEGGRFIEMGKADLRDPESVLAERGVVYRSYDLFEAGPDRIQQMLGEIVGLFEQGVLRSAPVRTWDVRQGREAFRFLREGRNTGKVVLTVPAPLDPDGTVLITGGTSGLGALFARHFVTAYDVRHLLLVSRRGSDADGVHQLVSDLEGRGCKVRVAACDVADRDQLAALLGSLDRPLTAVVHSAGVLADGLIETMTSEQVERVMRPKVDAAVHLHELTAGMDLAAFVLFSSVAALMGSPGQGNYAAANAFLDALAAHRRAAGLPATSLAWGMWAEGMAGTLDRAALARWARTGIEAFPAATGLALFDAAQRLGPAVVVPVELNRTTLRGQARTGTLAPLLRGLVRTPARRAVAGGSLAQRLAAVPVADREQVVRELVQAQVAAVLGHASPAAVEPGRAFKELGFDSLASVELRNRLVEATGLRLPSTLVFDHPTPQAVARLLVAEVAGEPAGSRVPDAPTGVDRRPRRARAGEPLAIVGMSCRFPGGVSSPEELWELVVNGRDAIGGLPADRGWDLDRLYDPDPDSLGTVSTRGGGFVSGVGDFDAGFFGIGPREAVAMDPQQRLLLEASWEALEDAGIDPTSLRGSDTGVFCGVVTSDYGPARPPELEGFRLTGSTSSVVSGRVAYTFGLQGPAVSVDTACSSSLVALHLAGQALRAGECSLALVAGVTVLAGPLLLQEFSRQRGLAPDGRCKPYAAAADGTGFSDGLGVILLERLSDAQRNGHRVLGVVRGSAVNQDGASNGLTAPNGPAQERVIRQALAVAGLSAAEVDVVEGHGTGTRLGDPIEAQALLATYGRDREVPLWLGSVKSNIGHTSAAAGVAGVIKMVQAMRYGVLPRTLHVDAPSPHVEWDAGRVELLTQARPWVVGGRPRRAGVSSFGISGTNAHVILEEAPRGDVEEAPRGEAEVESVVVPSVVPILVSARSEQALRAQEARLRAFLPGRDLLDVAFSAATTRAHLEYRVALVGEERFAGRPVVGKTAVLFTGQGSQRARMGAGLTYPVFRRVFDEVCGHFDPEVREALVSADGSGLDDTRVTQAALFAVEVALFRLVESFGVRPDFLLGHSVGELAAAHVAGVLSLVDACTLVAARGRLMGALPAGGGMLAVQATEDEISGVAVAAVNGPSAVVVSGSLDELREFQARWSDRKTTWLTVSHAFHSPLMEPMLEEFERVARGLDFRSPRIPIVSNVTGGVVGDEVTDPAYWVRHVREAVRFHDGVRTLREQGVTRFLELGPDAVLTAMARSFLDDDVVLAAALRAKQSEPHAFAAFLAQAHNAGVPVDWAAVLAGGKRIDLPTYAFQHQRYWLMPDTSSLDRVDHPLLTGAVRVGDRDEWVLTGRLSRDLAPWLPDHAVLGTVVVPGTALVELALTAGRHAGTPVVDELTLETPLVVPADAEVRLQVTVGEPGGDGRREVALYSAGPAGDGEPAVPVCHARGLLTATATATATATAEPAAAFPASWPPAGAEPVTADELYARLAAAGYQYGPAFQGVRTAWRTGEHVYAEVAHADATGGYTLHPALFDATLHSGLDWLDQGEDASAGLPFAWSGVSVDRPGPGHVRVRIGPAGPSAIRVDLADEHGAPVASVASLVVRPIDTGRLEAALRTRSDALFGIGWTPVAAPARNGGRPPRVVGLGGHRRVAEHYADLDTLDRALTEGAPVPDVVLLPAPAPAPGPAGPAEQAQAVAERTLSLVQQWLEIDRLAGARLVLTTRTAVAAGAEVPDLAQAPVWGLIRSAQSEHPGRFQLVDLEASADEPDCADEPEWAALSQLDEPQLAVRAGTLLAPRLTRTTAGPGAALPDLDPDGTVLITGGTGGLGAVLARHLAQRHGATRLLLVSRRGAAAPGAAELVAELAALGADARAVACDVADRDQLAALLADLDRPLTAVVHAAGVLDDGVVTSLSAEQLRRVMTPKVHAAVNLDELTAGHPVTAFVLFSSVAALIGSPGQANYAAANAVLDALAHRRRAAGLPGTSLAWGLWAEAGGMAGEISGADHARIQRLGVRALPTALGVDLFDQADALGAALLVPAQLDLAALRAQARAGTLLPLMRGLVAAPARHADDDTSFAQRLAGVTAAEREPIVLQLVQAQVAEVLGLAAAGAVDPGRAFKDLGFDSLGAVELRNRLTRATGVRLSSTLVFDYPTPAAIAALLLTELGGAEPAEPPIDQELRRLEDTLAGAGPADRQRAAAKLRTLLAAITGGEQRTSERIEAATTADEVLELINAEFGDV

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP058905
EMBL· GenBank· DDBJ
QLJ96953.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
FeedbackHelp