A0A7D5V8U5 · A0A7D5V8U5_9NEIS

  • Protein
    5-methylthioadenosine/S-adenosylhomocysteine deaminase
  • Gene
    mtaD
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L-homocysteine, respectively. Is also able to deaminate adenosine.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Catalytic activity

Cofactor

Zn2+ (UniProtKB | Rhea| CHEBI:29105 )

Note: Binds 1 zinc ion per subunit.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site67Zn2+ (UniProtKB | ChEBI)
Binding site69Zn2+ (UniProtKB | ChEBI)
Binding site96substrate
Binding site189substrate
Binding site216Zn2+ (UniProtKB | ChEBI)
Binding site219substrate
Binding site304Zn2+ (UniProtKB | ChEBI)
Binding site304substrate

GO annotations

AspectTerm
Molecular Function5'-methylthioadenosine deaminase activity
Molecular Functionmetal ion binding
Molecular FunctionS-adenosylhomocysteine deaminase activity

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    5-methylthioadenosine/S-adenosylhomocysteine deaminase
  • EC number
  • Short names
    MTA/SAH deaminase

Gene names

    • Name
      mtaD
    • ORF names
      HZU75_01170

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • STM-7
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Betaproteobacteria > Neisseriales > Chitinibacteraceae > Chitinibacter

Accessions

  • Primary accession
    A0A7D5V8U5

Proteomes

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain59-408Amidohydrolase-related

Sequence similarities

Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    442
  • Mass (Da)
    48,061
  • Last updated
    2021-02-10 v1
  • Checksum
    0D3843A82417E497
MSVQILLPRWIIPVIPRHTVYTDHALVIQGEKIIALQATADALSRYPSAEIIKLPDHALMPGMINLHTHSAMTLLRGFADDLPLMRWLNEHIWPAEGTHVSDEFVFDGTKLAIAEMIAGGTTCCNDMYFHHGAVARAAIDTQFRITVGCSILEFPTPYASNADDYIRKALACRDEFIGEDLVQFTLAPHAPYTVSDATFRRIITLADELELAIHCHIHESADEIAGSLKEYGVRPLERLAELGLLDSPLIAAHMVHTTESEIALLAKKGIHIAHNPASNLKLASGIAPISQQLAAGINVGIGTDGAASNNKLDMFAEMRLAALLAKGQSDNPEAVPAWQALEMATINGATALGLQDKIGSLEVGKQADVIALNLAQAGTQPCYDPISHLVYAADRTQVSDVWIAGRAVYRRHEHQSLNFAEVLSTARHWQGKIQDSIAPQTN

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP058952
EMBL· GenBank· DDBJ
QLI80253.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
FeedbackHelp