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A0A7D5TJ37 · A0A7D5TJ37_HUMAN

  • Protein
    NADH-ubiquinone oxidoreductase chain 6
  • Gene
    ND6
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    2/5

Function

function

Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.

Catalytic activity

GO annotations

AspectTerm
Cellular Componentmitochondrial inner membrane
Molecular FunctionNADH dehydrogenase (ubiquinone) activity

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    NADH-ubiquinone oxidoreductase chain 6
  • EC number

Gene names

    • Name
      ND6

Encoded on

  • Mitochondrion

Organism names

  • Taxonomic identifier
  • Organism
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Primates > Haplorrhini > Catarrhini > Hominidae > Homo

Accessions

  • Primary accession
    A0A7D5TJ37

Subcellular Location

Mitochondrion inner membrane
; Multi-pass membrane protein
Mitochondrion membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane25-46Helical
Transmembrane53-75Helical
Transmembrane81-106Helical

Keywords

PTM/Processing

Features

Showing features for signal, chain.

Type
IDPosition(s)Description
Signal1-15
ChainPRO_502787340216-163NADH-ubiquinone oxidoreductase chain 6

Proteomic databases

Interaction

Subunit

Core subunit of respiratory chain NADH dehydrogenase (Complex I) which is composed of 45 different subunits.

Family & Domains

Sequence similarities

Belongs to the complex I subunit 6 family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Fragment
  • Length
    163
  • Mass (Da)
    17,404
  • Last updated
    2020-12-02 v1
  • MD5 Checksum
    F93AEC71338AD2E37E5FD9256675F076
MMYALFLLSVGLVMGFVGFSSKPSPIYGGLVLIVSGVVGCVIILNFGGGYMGLMVFLIYLGGMMVVFGYTTAMAIEEYPEAWGSGVEVLVSVXXGLAMEVGLVLWVKEYDGVVVVVNFNSVGSWMIYEGEGSGLIREDPIGAGALYDYGRWLVVVTGWTLFVG

Features

Showing features for non-terminal residue.

TypeIDPosition(s)Description
Non-terminal residue163

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
MN687302
EMBL· GenBank· DDBJ
QLH92765.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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