A0A7D5K0M0 · A0A7D5K0M0_9MICO
- ProteinL-glutamate gamma-semialdehyde dehydrogenase
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids1154 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
Catalytic activity
- L-glutamate 5-semialdehyde + NAD+ + H2O = L-glutamate + NADH + 2 H+
Pathway
Amino-acid degradation; L-proline degradation into L-glutamate; L-glutamate from L-proline: step 2/2.
Features
Showing features for active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Active site | 721 | ||||
Active site | 755 | ||||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasmic side of plasma membrane | |
Molecular Function | 1-pyrroline-5-carboxylate dehydrogenase activity | |
Molecular Function | DNA-binding transcription factor activity | |
Molecular Function | proline dehydrogenase activity | |
Biological Process | proline catabolic process to glutamate |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameL-glutamate gamma-semialdehyde dehydrogenase
- EC number
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Actinomycetota > Actinomycetes > Micrococcales > Microbacteriaceae > Microbacterium
Accessions
- Primary accessionA0A7D5K0M0
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Structure
Family & Domains
Features
Showing features for domain, region, compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 149-432 | Proline dehydrogenase | |||
Region | 466-491 | Disordered | |||
Compositional bias | 474-491 | Polar residues | |||
Domain | 519-940 | Aldehyde dehydrogenase | |||
Sequence similarities
Belongs to the aldehyde dehydrogenase family.
Family and domain databases
Sequence
- Sequence statusComplete
- Length1,154
- Mass (Da)122,065
- Last updated2021-02-10 v1
- ChecksumB4938454B414B492
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 474-491 | Polar residues | |||
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CP058316 EMBL· GenBank· DDBJ | QLD13083.1 EMBL· GenBank· DDBJ | Genomic DNA |