A0A7C9LPT8 · A0A7C9LPT8_9BACT

  • Protein
    UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
  • Gene
    murF
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Pathway

Cell wall biogenesis; peptidoglycan biosynthesis.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site99-105ATP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular FunctionATP binding
Molecular FunctionUDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
Molecular FunctionUDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity
Biological Processcell division
Biological Processcell wall organization
Biological Processpeptidoglycan biosynthetic process
Biological Processregulation of cell shape

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
  • EC number
  • Alternative names
    • D-alanyl-D-alanine-adding enzyme

Gene names

    • Name
      murF
    • ORF names
      F0475_06820

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • A2879
  • Taxonomic lineage
    Bacteria > Bacteroidota > Bacteroidia > Bacteroidales > Prevotellaceae > Prevotella

Accessions

  • Primary accession
    A0A7C9LPT8

Proteomes

Subcellular Location

Keywords

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain16-83Mur ligase N-terminal catalytic
Domain97-291Mur ligase central
Domain315-428Mur ligase C-terminal

Sequence similarities

Belongs to the MurCDEF family. MurF subfamily.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    440
  • Mass (Da)
    49,198
  • Last updated
    2021-02-10 v1
  • Checksum
    44391E9F5E803B0C
MDIQEIYKIYLSHPTVTTDSRNCPEGSIFIALKGASFDGNKFAKAALDKGCSYAIVDEKEYIDTTDERFILVDDALVTYKELAREHRRQFSIPVIGITGTNGKTTSKELISTVLAEKYKVHHTEANYNNDVGVPRTLLGIRPDDEIAVIEMGASHPGDIEKLVTYVEPTCGLITNVGRAHLQGFGSFEGVKRTKGELYDFLKAHDALLFLNESNADLTEMAAQREFDRIITYGQDDTADVQGKVINCAPFLKFEWQSSSLNKQQPANTIYEVQTHLIGSYNLDNMLAAITIGLHFGVTPQQINHALENYIPHNNRSQLTETAHNKLIVDAYNANPSSMAAAIENFHLMEVEHKMAILGDMRELGAASAEEHQKVVELLKTAGLTNVWLVGEEFQKTNTDFRKFKDVDEVKAEIALHRPEDHYILIKGSNGIRLFELPNLL

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
VVIQ01000006
EMBL· GenBank· DDBJ
MUL28018.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
FeedbackHelp