A0A7C9HGE6 · A0A7C9HGE6_9BACT
- ProteinPeptide chain release factor 3
- GeneprfC
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids522 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 14-21 | GTP (UniProtKB | ChEBI) | |||
Binding site | 82-86 | GTP (UniProtKB | ChEBI) | |||
Binding site | 136-139 | GTP (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | GTP binding | |
Molecular Function | GTPase activity | |
Molecular Function | translation release factor activity, codon specific | |
Biological Process | regulation of translational termination |
Keywords
- Biological process
- Ligand
Names & Taxonomy
Protein names
- Recommended namePeptide chain release factor 3
- Short namesRF-3
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Bacteroidota > Bacteroidia > Bacteroidales > Prevotellaceae > Prevotella
Accessions
- Primary accessionA0A7C9HGE6
Proteomes
Subcellular Location
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 5-272 | Tr-type G | |||
Sequence similarities
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
Family and domain databases
Sequence
- Sequence statusComplete
- Length522
- Mass (Da)60,123
- Last updated2021-02-10 v1
- ChecksumD60FD1FB8124B6B4
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
VVIQ01000008 EMBL· GenBank· DDBJ | MUL28364.1 EMBL· GenBank· DDBJ | Genomic DNA |