A0A7C9HEZ1 · A0A7C9HEZ1_9BACT

  • Protein
    dTTP/UTP pyrophosphatase
  • Gene
    maf
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

a divalent metal cation (UniProtKB | Rhea| CHEBI:60240 )

Features

Showing features for site, active site.

TypeIDPosition(s)Description
Site13Important for substrate specificity
Active site72Proton acceptor
Site73Important for substrate specificity
Site155Important for substrate specificity

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular Functionnucleoside triphosphate diphosphatase activity
Biological Processnucleotide metabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    dTTP/UTP pyrophosphatase
  • EC number
  • Short names
    dTTPase/UTPase
  • Alternative names
    • Nucleoside triphosphate pyrophosphatase
    • Nucleotide pyrophosphatase
      (Nucleotide PPase
      )

Gene names

    • Name
      maf
    • ORF names
      F0475_10215

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • A2879
  • Taxonomic lineage
    Bacteria > Bacteroidota > Bacteroidia > Bacteroidales > Prevotellaceae > Prevotella

Accessions

  • Primary accession
    A0A7C9HEZ1

Proteomes

Subcellular Location

Keywords

Family & Domains

Sequence similarities

Belongs to the Maf family. YhdE subfamily.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    188
  • Mass (Da)
    21,181
  • Last updated
    2021-02-10 v1
  • Checksum
    8DD24FE5120E703D
MKKHIILASNSPRRRELLAGLDLDFEVKVLPDVAEDYPHDLPAVDVAGYIAREKADVYKAMITEEDLVITADTVVVVDNEVLGKPVDANDARRMLHLISGRKHQVVTGVCLLTSTDYHSFSVTTDVTFKKLSDEEINYYIEHFKPFDKAGAYGIQEWIGYVGVTSINGSYFNVMGLPVQRIWEEVHKL

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
VVIQ01000012
EMBL· GenBank· DDBJ
MUL28663.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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