A0A7C8YR97 · A0A7C8YR97_OPUST

Function

function

Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Note: Binds 1 Mg2+ ion per subunit.

Pathway

Purine metabolism; AMP biosynthesis via de novo pathway; AMP from IMP: step 1/2.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site139-145substrate
Binding site143IMP (UniProtKB | ChEBI)
Binding site145GTP (UniProtKB | ChEBI)
Binding site171-173GTP (UniProtKB | ChEBI)
Binding site254-256GTP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentchloroplast
Molecular Functionadenylosuccinate synthase activity
Molecular FunctionGTP binding
Molecular Functionmagnesium ion binding
Biological Process'de novo' AMP biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Adenylosuccinate synthetase, chloroplastic
  • EC number
  • Short names
    AMPSase
    ; AdSS
  • Alternative names
    • IMP--aspartate ligase

Gene names

    • Name
      PURA

Organism names

Accessions

  • Primary accession
    A0A7C8YR97

Subcellular Location

Keywords

Interaction

Subunit

Homodimer.

Family & Domains

Sequence similarities

Belongs to the adenylosuccinate synthetase family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    265
  • Mass (Da)
    29,188
  • Last updated
    2020-12-02 v1
  • Checksum
    370950722B9F6D26
MNPSTLRFDPSLICFTRSTHGLDRVPTHCRPWRVSTRSRRTTAVECSSVKSADSVAVTQQTRDGLSRIDGLSQVSGVLGCQWGDEGKGKLVDILAQHFDVVARCQVKAYTTRVGSGPFPTEILGQDGDLLRFAGQEFGTTTGRPRRCGWLDVVALKYSCQINGFSSLNLTKLDVLSDLSEIRLGVAYKDVDGTPIKSFPADLRVLERLKVEYEVLPGWKTDISSVRNYGDLPLAAQNYVERIEELVGIPVHYIGVGPGRDALIFK

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
GISG01048857
EMBL· GenBank· DDBJ
MBA4624738.1
EMBL· GenBank· DDBJ
Transcribed RNA

Similar Proteins

Disclaimer

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