A0A7C4Y522 · A0A7C4Y522_9BACT
- ProteinOxygen sensor histidine kinase NreB
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids187 (go to sequence)
- Protein existencePredicted
- Annotation score2/5
Function
function
Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT.
Catalytic activity
Cofactor
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Cellular Component | membrane | |
Molecular Function | 4 iron, 4 sulfur cluster binding | |
Molecular Function | metal ion binding | |
Molecular Function | phosphorelay sensor kinase activity | |
Molecular Function | protein dimerization activity |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameOxygen sensor histidine kinase NreB
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Bacteroidota > Bacteroidia
Accessions
- Primary accessionA0A7C4Y522
Subcellular Location
UniProt Annotation
GO Annotation
Cell membrane ; Multi-pass membrane protein
Keywords
- Cellular component
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 1-185 | Histidine kinase | ||||
Sequence: KQIMAASLMSLGFAKDSMKENPAVAVETIENVRDYIREAIQELRRLSHQLAPSADTNLPLAEKIRMLADNMNSAKSLDIHINVDDFDEPLHNDIQLAFYRILQEQLSNILKYAKATIAEIIIERADKNVMLTIRDNGKGFDTSVKKDGIGLENIKRRVNVIGGEAKIISSPGKGCSVVLKVPFGK |
Family and domain databases
Sequence
- Sequence statusFragment
- Length187
- Mass (Da)20,760
- Last updated2020-12-02 v1
- Checksum0AD9F1B79F2B755D
Features
Showing features for non-terminal residue.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Non-terminal residue | 1 | |||||
Sequence: K |