A0A719U1V9 · A0A719U1V9_SALTI

Function

function

Catalyzes the formation of a hydroxyacyl-CoA by addition of water on enoyl-CoA. Also exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Pathway

Lipid metabolism; fatty acid beta-oxidation.

Features

Showing features for site.

TypeIDPosition(s)Description
Site118Important for catalytic activity
Site140Important for catalytic activity

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular Function3-hydroxyacyl-CoA dehydrogenase activity
Molecular Function3-hydroxybutyryl-CoA epimerase activity
Molecular Functionenoyl-CoA hydratase activity
Molecular FunctionNAD+ binding
Biological Processfatty acid beta-oxidation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Fatty acid oxidation complex subunit alpha

Including 2 domains:

  • Recommended name
    Enoyl-CoA hydratase/3-hydroxybutyryl-CoA epimerase
  • EC number
  • Recommended name
    3-hydroxyacyl-CoA dehydrogenase
  • EC number

Gene names

    • Name
      fadJ
    • ORF names
      G1Y63_03875
      , G1Y70_03875

Organism names

Accessions

  • Primary accession
    A0A719U1V9

Subcellular Location

Keywords

Interaction

Subunit

Heterotetramer of two alpha chains (FadJ) and two beta chains (FadI).

Family & Domains

Features

Showing features for region, domain.

TypeIDPosition(s)Description
Region1-190Enoyl-CoA hydratase
Region306-7153-hydroxyacyl-CoA dehydrogenase
Domain311-4893-hydroxyacyl-CoA dehydrogenase NAD binding
Domain492-5863-hydroxyacyl-CoA dehydrogenase C-terminal

Sequence similarities

In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.
In the central section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    715
  • Mass (Da)
    77,235
  • Last updated
    2020-12-02 v1
  • Checksum
    91D34D2066E7B2A4
MTTTSAFMLNVRLDNVAVVAIDVPGEKVNTLKAEFAAQVRAILKQIRENKALQGVVFISAKADNFIAGADINIIGHCQNAQEAETLARQGQQLMAEIQALPVPVIAAIHGACLGGGLEMALACHRRICTDDVKTVLGLPEVQLGLLPGSGGTQRLPRLVGVSTALDMILIGKQLRARQALKAGLVDDVVPQTILLEAAVELAKKERLAQRTLPVRERILAGPLGRALLFRLVRKKTAQKTQGNYPATERIIDVIETGLAQGSSSGYDAEARAFGELAMTPQSQALRAVFFASTEVKKDPGSDAPPGPLNSVGILGGGLMGGGIAWVTACKGGLPVRIKDINTQGINHALKYSWDLLETKVRRRHIKASERDKQLALISGSTDYRGFSHRDLVIEAVFEDLPLKQQMVAEVEQNCATHTIFASNTSSLPIGDIAANAARPEQVIGLHFFSPVEKMPLVEVIPHASTSAQTIATTVKLAKKQGKTPIVVSDKAGFYVNRILAPYINEAIRMLTEGERVEHIDAALVKFGFPVGPIQLLDEVGIDTGTKIIPVLEAAYGERFSAPANVVASILNDDRKGRKNGRGFYLYGEKGRKSKKQVDPAIYKLIGVQGQSRLSAQQVAERCVMLMLNEAARCFDEKVIRSARDGDIGAVFGIGFPPFLGGPFRYMDALGPGEMVATLQRLAALYGPRYAPCEQLVRMAERREHFWTNGETDQGN

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
DAAPRH010000002
EMBL· GenBank· DDBJ
HAD7424424.1
EMBL· GenBank· DDBJ
Genomic DNA
DAAPSJ010000002
EMBL· GenBank· DDBJ
HAD7535875.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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